Eisuke Itakura

Name	Eisuke Itakura
URL
Affiliation	Chiba University
Section	大学院理学研究院　生物学研究部門
Job title
Degree	Doctor of Science(Saitama University)
J-Global ID	201901011463911905

Research Interests

細胞外環境 ,分子細胞生物学 ,エンドサイトーシス ,リソソーム ,メンブラントラフィック ,オートファジー ,タンパク質分解

Research Areas

Life sciences / Cell biology / タンパク質分解

Research History

Apr 2021

Today

Chiba University

Mar 2015

Mar 2021

千葉大学大学院理学研究院助教

Aug 2012

Feb 2015

MRC Laboratory of Molecular Biology (UK) 日本学術振興会海外特別研究員・研究員

Apr 2009

Jul 2012

Tokyo Medical and Dental University

Education

Apr 2006

Mar 2009

Saitama University Graduate School of Science and Engineering

Awards

12 >

Dec 2020

Journal of Cell Biology, The Year in Cell Biology 2020
Heparan sulfate is a clearance receptor for aberrant extracellular proteins. JCB 2020

2018

千葉大学, 千葉大学先進科学賞
板倉英祐

2017

日本生化学会, 奨励賞
板倉英祐

2017

文部科学省, 文部科学大臣表彰若手科学者賞
板倉英祐

2015

第67回日本細胞生物学会, 若手優秀発表賞
板倉英祐

Papers

12 3 4 5 >

A novel autophagy inhibitor, bTBT, disturbs autophagosome formation

Momoka Chiba Mai Yanagawa Yurika Oyama Shingo Harada Tetsuhiro Nemoto Akira Matsuura Eisuke Itakura

Autophagy Reports 2(1) Apr 2023 [Refereed]

Alpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded proteins

Ayaka Tomihari Mako Kiyota Akira Matsuura Eisuke Itakura

Scientific Reports Mar 2023 [Refereed]

CCPG1 recognizes ER luminal proteins for selective ER-phagy

Shunsuke Ishii Haruka Chino Koji L. Ode Yoshitaka Kurikawa Hiroki R. Ueda Akira Matsuura Noboru Mizushima Eisuke Itakura

Molecular Biology of the Cell Feb 2023 [Refereed]

The endoplasmic reticulum (ER) is a major cell compartment where protein synthesis, folding and post-translational modifications occur with assistance from a wide variety of chaperones and enzymes. Quality control systems selectively eliminate abn...

Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT

Yuki Date Akira Matsuura Eisuke Itakura

Cell Death Discovery 8(1) 37-37 Dec 2022 [Refereed]

Abstract

Autophagy plays important role in the intracellular protein quality control system by degrading abnormal organelles and proteins, including large protein complexes such as ribosomes. The eukaryotic chaperonin tailless complex polypeptide...

Protocol for quantification of the lysosomal degradation of extracellular proteins into mammalian cells.

Ayaka Tomihari Momoka Chiba Akira Matsuura Eisuke Itakura

STAR protocols 2(4) 100975-100975 Dec 2021 [Refereed]

Endocytic internalization of extracellular proteins plays roles in signaling, nutrient uptake, immunity, and extracellular protein quality control. However, there are few protocols for analyzing the lysosomal degradation of extracellular protein. ...