Researcher Search Results >> Takayoshi Arai

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Takayoshi Arai

Name	Takayoshi Arai
Alternative Names	T. Arai
URL	https://smarc.chiba-u.jp/socl/
Affiliation	Chiba University
Section	大学院理学研究院化学研究部門
Job title	professor
Degree	Ph.D.(Pharmaceutical Sciences)(The University of Tokyo)
Other Affiliation	ソフト分子活性化研究センター, 千葉ヨウ素資源イノベーションセンター
ORCID ID	0000-0001-9490-3988
J-Global ID	200901045434703168

Research Interests

触媒的不斉合成 Catalytic asymmetric synthesis ,Catalytic asymmetric synthesis

Research Areas

Life sciences / Bioorganic chemistry /
Nanotechnology/Materials / Structural/physical organic chemistry /

Awards

Apr 2021

ヨウ素学会, ヨウ素学会賞,ヨウ素の高機能化：ハロゲン結合によって駆動する協奏機能不斉触媒の開発
荒井孝義

Feb 2017

有機合成化学協会, 日産化学・有機合成新反応/手法賞,多様性窒素配位子-金属不斉触媒のテーラーメード開発による複雑系キラル分子の創製
荒井孝義

1995

有機合成化学協会研究企画賞

Papers

12 3 4 5 >

Halogenation/Cyanation vs. Cyanation/Halogenation of Alkenes Using ICN and BrCN

Ikumi Furusawa Takumi Suzuki Yan Yu Takayoshi Arai

Advanced Synthesis & Catalysis 365(19) 3247-3252 Jul 2023

Abstract

In a tris(pentafluorophenyl)borane [B(C₆F₅)₃]‐catalyzed reaction of alkenes with cyanogen halides (XCN), BrCN proceeds in a cyanation/bromination manner, in which a cationic CN character is realized. The ...

Asymmetric para-Selective aza-Friedel–Crafts Reaction of Phenols Catalyzed by Bulky PyBidine-Ni(OAc)₂

Ryoya Tajima Takaaki Saito Takayoshi Arai

ACS Catalysis 13(14) 9495-9501 Jul 2023

Successful Identification of a Novel Therapeutic Compound for Hepatocellular Carcinoma Through Screening of ADAM9 Inhibitors

KEITA OGAWA TETSUHIRO CHIBA MASATO NAKAMURA JUN ARAI JIAQI ZHANG YAOJIA MA NA QIANG JUNJIE AO SAE YUMITA TAKAMASA ISHINO MOTOYASU KAN TERUNAO IWANAGA MIYUKI NAKAGAWA KISAKO FUJIWARA TAKAFUMI SAKUMA HIROAKI KANZAKI KEISUKE KOROKI YUKO KUSAKABE KAZUFUMI KOBAYASHI NAOYA KANOGAWA SOICHIRO KIYONO TAKAYUKI KONDO RYO NAKAGAWA SADAHISA OGASAWARA RYOSUKE MUROYAMA SHINGO NAKAMOTO TATSUO KANDA HITOSHI MARUYAMA JUN KATO SHOJI MATSUMOTO TAKAYOSHI ARAI SHINICHIRO MOTOHASHI NAOYA KATO

Anticancer Research 43(3) 1043-1052 Feb 2023

Asymmetric Friedel–Crafts-Type Reaction of 2-Vinylindoles to N-Boc Imines Using a Chiral Imidazolidine-Containing NCN-Pincer Pd Catalyst

Tomoya Yokota Hyuma Masu Takayoshi Arai

The Journal of Organic Chemistry 88(12) 7872-7881 Feb 2023

Development of a novel light-up probe for detection of G-quadruplexes in stress granules.

Keisuke Iida Natsumi Suzuki Ayano Sasaki Shunsuke Ishida Takayoshi Arai

Scientific reports 12(1) 12892-12892 Jul 2022

G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small molecules has been poorly investigated. Herein, we present a fluorescent light-up pro...

Misc.

12 3 4 5 >

Notchシグナル阻害作用を有する光学活性スピロオキシインドール誘導体の創成研究

荒井緑荒井緑川野はるか荒井孝義荒井孝義荒井孝義石橋正己石橋正己

シンポジウム「モレキュラー・キラリティー」講演要旨集 2019 136‐137 Jun 2019

千葉化合物ライブラリーからのAscl1発現モジュレーターの創製

本山あゆみ荒井緑荒井孝義影山龍一郎石橋正己

日本薬学会年会要旨集(CD-ROM) 139th ROMBUNNO.22PO‐am105S 2019

新規フェニル化合物CCL360、CCL361によるG2/M期停止とアポトーシス誘導(G2/M phase arrest and apoptosis induced by novel phenyl compounds, CCL360 and CCL361)

齋藤謙悟大野吉史 Vahed Majid 李斉森郭書翰馬雪菅波晃子田村裕荒井孝義白澤浩

日本癌学会総会記事 77回 621-621 Sep 2018

神経再生医薬を目指したスピロ型Notchシグナル阻害剤の創製

荒井緑荒井緑岡野美優川野はるか荒井孝義荒井孝義石橋正己石橋正己

複素環化学討論会講演要旨集 48th 147 Aug 2018

新規化合物CCL441は細胞周期をG2/M期で停止させアポトーシスを誘導する

坪坂歩大野吉史李斉森馬雪郭書翰蟻瑞栄中本晋吾齋藤謙悟菅波晃子田村裕土田晃子荒井孝義白澤浩

日本癌学会総会記事 76回 P-3356 Sep 2017

Professional Memberships

12 >

American Chemical Society

The Society of Iodine Science

日本化学会

日本希土類学会

有機合成化学協会

Research Projects

12 3 4 5 >

クーロン相互作用選択的活性化による新規分子変換法
日本学術振興会: 科学研究費助成事業挑戦的研究(開拓)
荒井孝義

Project Year: Jul 2021 - Mar 2025

Dynamic Stereochemical Control of Halogen Bonding in Reaction Sphere
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

Project Year: Apr 2019 - Mar 2023

Advanced stereoselective catalysis on the composite metal reaction sphere
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Project Year: Apr 2018 - Mar 2020

多金属高活性反応場による低分子量分子ジョイント化学
日本学術振興会: 科学研究費助成事業新学術領域研究(研究領域提案型)
荒井孝義

Project Year: Apr 2016 - Mar 2018

Creation of regeneration accelerating molecules using target protein oriented natural products isolation (TPO-NAPI)
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
Arai Midori ISHIBASHI Masami KOUDA Masao TAMURA Yutaka ARAI Takayoshi

Project Year: Apr 2015 - Mar 2018