川波 亜紀子

BACKGROUND: Mother-to-infant bonding (MIB) is critical for the health and well-being of the mother and child. Furthermore, MIB has been shown to boost the social-emotional development of infants, while also giving mothers a sense of happiness in raising their children. Nausea and vomiting during pregnancy (NVP) is a normal complication of pregnancy, occurring in approximately 50-90% of pregnant women in the early stages of pregnancy. Despite widespread knowledge of MIB and postpartum depression, little research attention has been given to the effects of NVP on MIB. This study aimed to investigate the relationship between NVP and MIB and the mediating effects of postpartum depression. METHODS: We analyzed the data of 88,424 infants and 87,658 mothers from the Japan Environment and Children's Study (JECS), which is a government-funded nationwide birth prospective cohort study. The Japanese version of the Mother-to-Infant Bonding Scale (MIBS-J) was used to assess MIB, and the Edinburgh Postpartum Depression Scale (EPDS) was utilized to assess postpartum depression. We divided participants into four groups according to a self-reported questionnaire assessing NVP (No NVP, Mild NVP, Moderate NVP, and Severe NVP). MIB disorder was defined as a MIBS-J score ≥ 5. Logistic analysis was performed to evaluate the effect of NVP on MIB disorder at one year after delivery. A mediation analysis was conducted to examine whether postpartum depression mediated the association between NVP and MIBS-J scores. RESULTS: The logistic regression analysis results revealed reduced risks of MIB disorder among mothers with Moderate NVP (adjusted OR 0.93; 95% confidence interval, 0.86-0.99) and Severe NVP (adjusted OR 0.81; 95% confidence interval, 0.74-0.89), compared to those with No NVP. The mediation analysis revealed that NVP positively correlated with MIBS-J score in the indirect effect via postpartum depression, while NVP (Mild NVP, Moderate NVP, and Severe NVP) negatively correlated with MIBS-J score in the direct effect. CONCLUSION: The risks of MIB disorder were reduced in the Moderate NVP and Severe NVP mothers, although NVP inhibited the development of MIB via postpartum depression. The development of effective interventions for postpartum depression is important to improve MIB among mothers with NVP.

type:text [要旨]2022年9月，千葉大学予防医学センターはコロナ禍の中断を経て3年ぶりに海外研修を再開した。「新規感染症とワンヘルス」を研修のテーマとし，本学大学院医学薬学府，看護学研究科等の学生と教職員総勢約27名が参加した。9月20日から23日までスイス・ジュネーブを訪れ，世界保健機関(World Health Organization: WHO)本部の視察にはじまり，全部で7つの国際機関の日本人職員等から各機関の役割や課題等について話を聞いた。9月26日から29日まではドイツ・ベルリンを訪れ，予防医学センターとシャリテ・ベルリン医科大学の共催による日独集中講義，および在ドイツ日本国大使館の支援による日独シンポジウムを開催し，公衆衛生や感染症の専門家による講演や活発なディスカッションが行われた。かつて森鷗外がドイツから日本に取り入れた公衆衛生の歴史を振り返ると共に，現代の脅威である新型コロナウイルス感染症(COVID-19)への各国の取り組みを学び，新規感染症発生の背景にある，人・動物・環境の生態系のバランスと健康を維持するワンヘルス・アプローチの重要性を認識した。参加者が本研修で学んだことを生かし，将来広い視野をもって国際保健の問題に取り組まれることを期待する。

type:text [要旨] 千葉大学では世界を視野に入れ多種多様な考えを理解し，対応できるグローバルな人材育成のため，国際化の推進を行っている。特にヨーロッパにおいてはドイツ連邦共和国の首都であるベルリンのCharit?-Universit?tsmedizin Berlin （シャリテ・ベルリン医科大学）と2010年に5 年間の大学間交流協定を締結して連携活動が始まり，2015年にはさらに2020年まで更新された。2015年にはシャリテ内に千葉大学ジャーマンセンターベルリンオフィスを開設し，両大学長の相互訪問やシンポジウム開催，共同研究の立ち上げなどを進めている。小論では特に最近3 年間の活動を中心に千葉大学とシャリテの共同作業について研究，教育分野などの現状と将来の展望をまとめた。 [SUMMARY] Chiba University is promoting internationalization in order to develop global human resources that can respond to and understand a wide variety of ideas with a view of the world. Especially in Europe, the first agreement was concluded in 2010 with the Charit?-Universit?tsmedizin Berlin, the capital of Germany Federal Republic, and the cooperation activities were carried out. In 2015, the first period of five years ended, and now the second phase（2015 to 2020）is running. In 2015, we established the Chiba University German Center Berlin Office in the Charit? and are working on a more active partnership.This paper summarizes the current activities and future prospects of the joint work of the Chiba University and the Charit? in the field of research and education,especially in the recent two-year activities.