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  2. 平野 好幸

平野 好幸

ヒラノ ヨシユキ  (Yoshiyuki Hirano)

基本情報

所属
千葉大学 子どものこころの発達教育研究センター 教授
国立研究開発法人量子科学技術研究開発機構
学位
博士
研究者番号
50386843
ORCID ID
 https://orcid.org/0000-0003-3844-3061
J-GLOBAL ID
201401006420535500
researchmap会員ID
B000238228
外部リンク

研究キーワード

 9

研究分野

 3

経歴

 12

受賞

 7
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論文

 140
  • Tomoko Kawasaki, Yoshikazu Noda, Yoshiyuki Hirano, Akiko Kawanami, Kenichi Sakurai, Chisato Mori, Eiji Shimizu
    Heliyon 2025年2月  
  • Jun Kanzawa, Ryo Kurokawa, Tsunehiko Takamura, Nobuhiro Nohara, Kouhei Kamiya, Yoshiya Moriguchi, Yasuhiro Sato, Yumi Hamamoto, Tomotaka Shoji, Tomohiko Muratsubaki, Motoaki Sugiura, Shin Fukudo, Yoshiyuki Hirano, Yusuke Sudo, Rio Kamashita, Sayo Hamatani, Noriko Numata, Koji Matsumoto, Eiji Shimizu, Naoki Kodama, Shingo Kakeda, Masatoshi Takahashi, Satoru Ide, Kazumasa Okada, Shu Takakura, Motoharu Gondo, Kazufumi Yoshihara, Masanori Isobe, Keima Tose, Tomomi Noda, Ryo Mishima, Michiko Kawabata, Shun'ichi Noma, Toshiya Murai, Kazuhiro Yoshiuchi, Atsushi Sekiguchi, Osamu Abe
    NeuroImage. Clinical 45 103737-103737 2025年1月29日  
    Anorexia nervosa (AN) is a severe eating disorder characterized by intense fear of weight gain, distorted body image, and extreme food restriction. This research employed advanced diffusion MRI techniques including single-shell 3-tissue constrained spherical deconvolution, anatomically constrained tractography, and spherical deconvolution informed filtering of tractograms to analyze brain network alterations in AN. Diffusion MRI data from 81 AN patients and 98 healthy controls were obtained. The structural brain connectome was constructed based on nodes set in 84 brain regions, and graph theory analysis was conducted. Results showed that AN patients exhibited significantly higher clustering coefficient and local efficiency in several brain regions, including the left fusiform gyrus, bilateral orbitofrontal cortex, right entorhinal cortex, right lateral occipital gyrus, right superior temporal gyrus, and right insula. A trend towards higher global efficiency and small-worldness was also observed in AN patients, although not statistically significant. These findings suggest increased local connectivity and efficiency within regions associated with behavioral rigidity, emotional regulation, and disturbed body image among AN patients. This study contributes to the understanding of the neurological basis of AN by highlighting structural connectivity alterations in specific brain regions.
  • Kentaro Araki, Yoshiyuki Hirano, Kohei Kurita, Eiji Shimizu
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 34(2) 108217-108217 2024年12月28日  
    OBJECTIVE: Non-verbal Screening Test for Aphasia and Dysarthria scores correlate with post-stroke cognitive function; however, their correlations with activities of daily living dependency and home discharge (cognitive function-associated outcomes) remain unclear. We investigated the correlation of these scores with activities of daily living dependency and home discharge outcomes. MATERIALS AND METHODS: Disability levels and functional outcomes of 278 inpatients with brain injury (age: 72.8 ± 13.0 years) were evaluated using the modified Rankin Scale. Patients were grouped according to activities of daily living dependency (independent [n = 96; modified Rankin Scale score≤2]) and non-home discharge (n = 126) status. Factors predicting home discharge were analyzed using univariate and multivariate logistic regression analyses. RESULTS: Cognitive impairment was more prevalent in the activities of daily living-dependent group than in the independent group (odds ratio: 6.34 [95 % confidence interval: 3.57-11.52]; p < 0.001) and in the non-home discharge than in the home discharge group (2.78 [1.65-4.73]; p < 0.001). Non-verbal test scores correlated moderately with activities of daily living independence and home discharge. Age, modified Rankin Scale score, cognitive impairment, and the Screening Test for Aphasia and Dysarthria scores were significantly associated with home discharge in univariate analyses. Only modified Rankin Scale and non-verbal test scores were significantly associated with home discharge in multivariate analysis (p < 0.001). CONCLUSIONS: Non-verbal test scores were significantly associated with activities of daily living independence and home discharge in patients with stroke. The non-verbal test, being less influenced by communicative disorders, offers a novel tool for estimating cognitive function.
  • Laura S van Velzen, Lejla Colic, Zuriel Ceja, Maria R Dauvermann, Luca M Villa, Hannah S Savage, Yara J Toenders, Niousha Dehestani, Alyssa H Zhu, Adrian I Campos, Lauren E Salminen, Ingrid Agartz, Nina Alexander, Rosa Ayesa-Arriola, Elizabeth D Ballard, Nerisa Banaj, Carlotta Barkhau, Zeynep Başgöze, Jochen Bauer, Francesco Benedetti, Klaus Berger, Bianca Besteher, Katharina Brosch, Manuel Canal-Rivero, Simon Cervenka, Romain Colle, Colm G Connolly, Emmanuelle Corruble, Philippe Courtet, Baptiste Couvy-Duchesne, Benedicto Crespo-Facorro, Kathryn R Cullen, Udo Dannlowski, Jeremy Deverdun, Ana M Diaz-Zuluaga, Lorielle M F Dietze, Jennifer W Evans, Negar Fani, Kira Flinkenflügel, Naomi P Friedman, Ian H Gotlib, Nynke A Groenewold, Dominik Grotegerd, Tomas Hajek, Alexander S Hatoum, Marco Hermesdorf, Ian B Hickie, Yoshiyuki Hirano, Tiffany C Ho, Yuki Ikemizu, Frank Iorfino, Jonathan C Ipser, Yuko Isobe, Andrea P Jackowski, Fabrice Jollant, Tilo Kircher, Melissa Klug, Sheri-Michelle Koopowitz, Anna Kraus, Axel Krug, Emmanuelle Le Bars, Elisabeth J Leehr, Meng Li, Elizabeth T C Lippard, Carlos Lopez-Jaramillo, Ivan I Maximov, Andrew M McIntosh, Katie A McLaughlin, Sean R McWhinney, Susanne Meinert, Elisa Melloni, Philip B Mitchell, Benson Mwangi, Igor Nenadić, Stener Nerland, Emilie Olie, Victor Ortiz-García de la Foz, Pedro M Pan, Fabricio Pereira, Fabrizio Piras, Federica Piras, Sara Poletti, Andrew E Reineberg, Gloria Roberts, Rafael Romero-García, Matthew D Sacchet, Giovanni A Salum, Anca-Larisa Sandu, Carl M Sellgren, Eiji Shimizu, Harry R Smolker, Jair C Soares, Gianfranco Spalletta, J Douglas Steele, Frederike Stein, Dan J Stein, Benjamin Straube, Lea Teutenberg, Florian Thomas-Odenthal, Paula Usemann, Romain Valabregue, Johanna Valencia-Echeverry, Gerd Wagner, Gordon Waiter, Martin Walter, Heather C Whalley, Mon-Ju Wu, Tony T Yang, Carlos A Zarate, Andre Zugman, Giovana B Zunta-Soares, Kees van Heeringen, Sanne J H van Rooij, Nic van der Wee, Steven van der Werff, Paul M Thompson, Hilary P Blumberg, Anne-Laura van Harmelen, Miguel E Rentería, Neda Jahanshad, Lianne Schmaal
    medRxiv : the preprint server for health sciences 2024年11月7日  
    Previous studies have suggested that alterations in white matter (WM) microstructure are implicated in suicidal thoughts and behaviours (STBs). However, findings of diffusion tensor imaging (DTI) studies have been inconsistent. In this large-scale mega-analysis conducted by the ENIGMA Suicidal Thoughts and Behaviours (ENIGMA-STB) consortium, we examined WM alterations associated with STBs. Data processing was standardised across sites, and resulting WM microstructure measures (fractional anisotropy, axial diffusivity, mean diffusivity and radial diffusivity) for 25 WM tracts were pooled across 40 cohorts. We compared these measures among individuals with a psychiatric diagnosis and lifetime history of suicide attempt (n=652; mean age=35.4±14.7; female=71.8%), individuals with a psychiatric diagnosis but no STB (i.e., clinical controls; n=1871; mean age=34±14.8; female=59.8%), and individuals with no mental disorder diagnosis and no STB (i.e., healthy controls; n=642; mean age=29.6±13.1; female=62.9%). We also compared these measures among individuals with recent suicidal ideation (n=714; mean age=36.3±15.3; female=66.1%), clinical controls (n=1184; mean age=36.8±15.6; female=63.1%), and healthy controls (n=1240; mean age= 31.6±15.5; female=61.0%). We found subtle but statistically significant effects, such as lower fractional anisotropy associated with a history of suicide attempt, over and above the effect of psychiatric diagnoses. These effects were strongest in the corona radiata, thalamic radiation, fornix/stria terminalis, corpus callosum and superior longitudinal fasciculus. Effect sizes were small (Cohen's d < 0.25). Recent suicidal ideation was not associated with alterations in WM microstructure. This large-scale coordinated mega-analysis revealed subtle regional and global alterations in WM microstructure in individuals with a history of suicide attempt. Longitudinal studies are needed to confirm whether these alterations are a risk factor for suicidal behaviour.
  • 李 敏, 岩谷 祥子, 平田 郁子, 橘 雅弥, 毛利 育子, 平野 好幸, 水野 賀史, 下野 九理子
    日本脳科学会プログラム・抄録集 51回 28-28 2024年11月  
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MISC

 104
  • Yumi Hamamoto, Yasuhiro Sato, Tsunehiko Takamura, Jeyoon Choi, Motoaki Sugiura, Yoshiyuki Hirano, Yusuke Sudo, Eiji Shimizu, Noriko Numata, Rio Kamashita, Koji Matsumoto, Naoki Kodama, Satoru Ide, Kazumasa Okada, Yuko Hirano, Masatoshi Takahashi, Nobuhiro Nohara, Yukari Yamanaka, Mikiko Matsuoka, Kazuhiro Yoshiuchi, Ruri Katsunuma, Motoharu Gondo, Shu Takakura, Kazufumi Yoshihara, Tomomi Noda, Keima Tose, Kana Morimoto, Momo Sunada, Momoka Taniguchi, Masanori Isobe, Shin Fukudo, Atsushi Sekiguchi
    PSYCHOTHERAPY AND PSYCHOSOMATICS 93 102-102 2024年8月  
  • 枡田 大生, 森 雅裕, 平野 成樹, 鵜沢 顕之, 内田 智彦, 武藤 真弓, 大谷 龍平, 青木 玲二, 青山 辰次, 平野 好幸, 桑原 聡
    神経免疫学 28(1) 201-201 2023年9月  
  • 大田淳子, 大田淳子, 佐々木翼, 佐々木翼, RITU Bhusal Chhatkuli, RITU Bhusal Chhatkuli, 鎌下莉緒, 鎌下莉緒, 吉田斎子, 栗田幸平, 栗田幸平, 荒木謙太郎, 大平育世, 大場久照, 清水栄司, 清水栄司, 清水栄司, 清水栄司, 平野好幸, 平野好幸, 平野好幸
    日本不安症学会学術大会プログラム・抄録集 15th 2023年  
  • 池水結輝, 池水結輝, 太田淳子, 太田淳子, ブーサル チャタクリリトゥ, ブーサル チャタクリリトゥ, 栗田幸平, 栗田幸平, 佐々木翼, 佐々木翼, 鎌下莉緒, 鎌下莉緒, 磯部祐子, 磯部祐子, 須藤佑輔, 須藤佑輔, 吉田斎子, 松本浩史, 桝田喜正, 加藤奈子, 中川彰子, 清水栄司, 清水栄司, 清水栄司, 清水栄司, 平野好幸, 平野好幸, 平野好幸
    日本不安症学会学術大会プログラム・抄録集 15th 2023年  
  • 須藤佑輔, 須藤佑輔, 大田淳子, 大田淳子, 鎌下莉緒, RITU Bhusal Chhatkuli, RITU Bhusal Chhatkuli, 濱谷沙世, 濱谷沙世, 高橋純平, 沼田法子, 吉田斎子, 北川等美, 清水栄司, 松本浩史, 桝田喜正, 中里道子, 佐藤康弘, 磯部昌憲, 兒玉直樹, 吉原一文, 高村恒人, 守口善也, 関口敦, 平野好幸, 平野好幸
    日本摂食障害学会学術集会プログラム・講演抄録集 25th 2022年  
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講演・口頭発表等

 12
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所属学協会

 7
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共同研究・競争的資金等の研究課題

 11
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社会貢献活動

 2
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