研究者業績

猪狩 英俊

イガリ ヒデトシ  (Hidetoshi Igari)

基本情報

所属
千葉大学 医学部附属病院 感染制御部 教授 (感染制御部長)
学位
医学博士

J-GLOBAL ID
200901048909387877
researchmap会員ID
1000284759

研究キーワード

 2

学歴

 2

論文

 130
  • Misuzu Yahaba, Haruna Asano, Kengo Saito, Shota Murata, Kenji Kawasaki, Hitoshi Chiba, Shou Yokota, Hiroshi Yoshikawa, Yoriko Herai, Kazutaka Yamagishi, Yuki Shiko, Kazuyuki Matsushita, Hideki Hanaoka, Toshibumi Taniguchi, Koutaro Yokote, Hiroshi Nakajima, Eiji Ido, Hidetoshi Igari
    Japanese journal of infectious diseases 2024年11月29日  
    The effect of antibodies elicited by bivalent mRNA vaccines (original and omicron BA.1) on preventing coronavirus disease 2019 (COVID-19) onset in the presence of the XBB variant remains unknown. A prospective cohort study conducted at Chiba University Hospital examined healthcare workers who received their sixth vaccination with the Pfizer-BioNTech COVID-19 bivalent mRNA vaccine (original and omicron BA.1). Researchers quantitatively measured serum anti-spike (S) antibody levels. Participants not infected during the 60-day observation period after vaccination had significantly higher S antibody titers than those who were newly infected (27756 U/mL, 95% CI [24988-30831 U/mL] vs. 15321 U/mL, 95% CI [10824-21688 U/mL], p<0.05). The risk of infection decreased by 84% when the S antibody titer exceeded 15500 U/ml. Neutralizing antibody titers against the XBB.1.16 and XBB.1.42 variants were higher in age- and sex-matched noninfected individuals than in newly infected individuals during the post-vaccination observation period. S antibody titers were highly correlated with neutralizing antibody titers. In conclusion, after the sixth COVID-19 vaccination with the bivalent mRNA vaccine (original and omicron BA.1), high S antibody titers correlated with disease prevention, even in the presence of XBB variants.
  • Yuriko Yamazaki, Tomoka Ito, Seitaro Nakagawa, Takashi Sugihira, Chinami Kurita-Tachibana, Amer E. Villaruz, Kensuke Ishiguro, Barbora Salcman, Shuo Li, Sanami Takada, Naohiro Inohara, Yoko Kusuya, Aki Shibata, Masakazu Tamai, Reika Aoyama, Kanako Inoue, Shota Murata, Kazuyuki Matsushita, Akiko Miyabe, Toshibumi Taniguchi, Hidetoshi Igari, Naruhiko Ishiwada, Masateru Taniguchi, Taka-Aki Nakada, Hiroyuki Matsue, Manabu Fujimoto, Haruka Hishiki, Yoshiteru Osone, Hiromichi Hamada, Naoki Shimojo, Tsutomu Suzuki, Michael Otto, Gabriel Núñez, Hiroki Takahashi, Akiko Takaya, Yuumi Nakamura
    Nature Communications 15(1) 2024年11月7日  
  • 新津 富央, 伊豫 雅臣, 橋本 謙二, 花岡 英紀, 藤原 忠美, 猪狩 英俊, 谷口 俊文, 中田 孝明, 鈴木 拓児, 吉村 健佑
    千葉医学雑誌 100(4) 108-108 2024年9月  
  • 椎野 禎一郎, 潟永 博之, 今橋 真弓, 渡邊 大, 南 留美, 蜂谷 敦子, 西澤 雅子, 林田 庸総, 吉田 繁, 豊嶋 崇徳, 伊藤 俊広, 古賀 道子, 貞升 健志, 佐野 貴子, 宇野 俊介, 谷口 俊文, 猪狩 英俊, 寒川 整, 中島 秀明, 吉野 友祐, 堀場 昌英, 茂呂 寛, 渡邉 珠代, 阪野 文哉, 川畑 拓也, 藤井 輝久, 高田 清式, 中村 麻子, 仲村 秀太, 松下 修三, 吉村 和久, 杉浦 亙, 菊地 正
    日本エイズ学会誌 26(3) 139-150 2024年8月  査読有り
  • 谷中 マリ, 谷口 俊文, 千葉 均, 漆原 節, 矢幅 美鈴, 猪狩 英俊
    日本環境感染学会総会プログラム・抄録集 39回 293-293 2024年7月  

MISC

 134
  • 猪狩英俊
    臨床と微生物 51 2024年1月  筆頭著者
  • 田代萌, 谷口俊文, 伊藤菜穂子, 渡邉未来, 猪狩英俊
    日本エイズ学会誌 25(2) 76-83 2023年5月31日  
  • 猪狩 英俊
    感染と消毒 30(1) 62-65 2023年5月  
    ISSN 1346-2326 ISSN-L 1346-2326
  • Shuhei Nagai, Hidemi Niwa, Yuki Terajima, Hiroki Igari, Young-Chang P. Arai, Toshihiko Yamashita, Toshihiko Taguchi, Masaya Nakamura, Takahiro Ushida
    Journal of Clinical Medicine 12(4) 1324-1324 2023年2月7日  
    Background: Numbness is a term commonly used in clinical practice to describe an abnormal sensory experience that is produced by a stimulus or is present even without a stimulus. However, there is still much that remains obscure in this field, and also, few reports have focused on its symptoms. In addition, while pain itself is known to have a significant impact on quality of life (QOL), the relationship between numbness and QOL is often unclear. Therefore, we conducted an epidemiological survey and analyzed the relationship between painless numbness and QOL, using type, location, and age as influencing factors, respectively. Methods: A nationwide epidemiological survey was conducted by mail using a survey panel designed by the Nippon Research Center. Questionnaires were sent to 10,000 randomly selected people aged 18 and over from all over Japan. Out of the 5682 people who responded, the relationship between numbness and QOL was analyzed using the EuroQol 5 Dimension-3L (EQ5D-3L) for patients who are currently experiencing painless numbness. Findings: The results suggest that painless numbness affects QOL and that QOL decreases as its intensity increases. Furthermore, the two factors of numbness of feet and numbness among the young may be less likely to affect QOL. This study may be of great significance in the field of numbness research.
  • 今泉優理, 石毛崇之, 藤川樹, 庭野亜美, 宮部安規子, 村田正太, 川崎健治, 西村基, 谷口俊文, 猪狩英俊, 松下一之
    日本遺伝子診療学会大会プログラム・抄録集 30th 2023年  

書籍等出版物

 18

講演・口頭発表等

 52

共同研究・競争的資金等の研究課題

 11

社会貢献活動

 41

メディア報道

 15