研究者業績

川﨑 剛

カワサキ タケシ  (Kawasaki Takeshi)

基本情報

所属
千葉大学 大学院医学研究院 呼吸器内科学 助教
学位
医学博士(千葉大学)
医学学士(東北大学)

連絡先
kawatakechiba-u.jp
研究者番号
20586383
J-GLOBAL ID
202001011689992038
researchmap会員ID
B000382279

主要な論文

 59
  • Huda Asif, Franck F Rahaghi, Akihiro Ohsumi, Julie Philley, Amir Emtiazjoo, Takashi Hirama, Arthur W Baker, Chin-Chung Shu, Fernanda Silveira, Vincent Poulin, Pete Rizzuto, Miki Nagao, Pierre-Régis Burgel, Steve Hays, Timothy Aksamit, Takeshi Kawasaki, Charles Dela Cruz, Stefano Aliberti, Takahiro Nakajima, Stephen Ruoss, Theodore K Marras, Gregory I Snell, Kevin Winthrop, Mehdi Mirsaeidi
    ERJ open research 9(2) 2023年3月  査読有り
    RATIONALE: Nontuberculous mycobacterial (NTM) diseases are difficult-to-treat infections, especially in lung transplant (LTx) candidates. Currently, there is a paucity of recommendations on the management of NTM infections in LTx, focusing on Mycobacterium avium complex (MAC), M. abscessus and M. kansasii. METHODS: Pulmonologists, infectious disease specialists, LTx surgeons and Delphi experts with expertise in NTM were recruited. A patient representative was also invited. Three questionnaires comprising questions with multiple response statements were distributed to panellists. Delphi methodology with a Likert scale of 11 points (5 to -5) was applied to define the agreement between experts. Responses from the first two questionnaires were collated to develop a final questionnaire. The consensus was described as a median rating >4 or <-4 indicating for or against the given statement. After the last round of questionnaires, a cumulative report was generated. RESULTS: Panellists recommend performing sputum cultures and a chest computed tomography scan for NTM screening in LTx candidates. Panellists recommend against absolute contraindication to LTx even with multiple positive sputum cultures for MAC, M. abscessus or M. kansasii. Panellists recommend MAC patients on antimicrobial treatment and culture negative can be listed for LTx without further delay. Panellists recommend 6 months of culture-negative for M. kansasii, but 12 months of further treatment from the time of culture-negative for M. abscessus before listing for LTx. CONCLUSION: This NTM LTx study consensus statement provides essential recommendations for NTM management in LTx and can be utilised as an expert opinion while awaiting evidence-based contributions.

MISC

 157

書籍等出版物

 1

講演・口頭発表等

 29

担当経験のある科目(授業)

 3

共同研究・競争的資金等の研究課題

 9