研究者業績

佐粧 孝久

サショウ タカヒサ  (Takahisa Sasho)

基本情報

所属
千葉大学 予防医学センター・運動器疼痛疾患学 教授
学位
医学博士(1996年3月 千葉大学大学院)

連絡先
sashofaculty.chiba-u.jp
J-GLOBAL ID
200901083280552594
researchmap会員ID
1000284764

外部リンク

論文

 415
  • Shotaro Watanabe, Takuya Sakamoto, Manato Horii, Seiji Kimura, Satoshi Yamaguchi, Seiji Ohtori, Takahisa Sasho
    Orthopaedic journal of sports medicine 13(1) 23259671241307672-23259671241307672 2025年1月  
    BACKGROUND: The factors contributing to osteoarthritis progression after anterior cruciate ligament (ACL) injury and reconstruction (ACLR) are not fully understood. Quantitative magnetic resonance imaging (MRI) offers a noninvasive way to evaluate cartilage biochemical composition using T1ρ mapping, thereby detecting early cartilage degeneration. The specific impact of preoperative quantitative MRI on long-term outcomes after ACLR remains underreported. PURPOSE/HYPOTHESIS: The purpose of this study was to investigate the effects of various factors, including preoperative cartilage T1ρ values, on the 10-year outcomes after ACLR. It was hypothesized that individual differences in baseline cartilage degeneration would influence osteoarthritis progression at 10 years postoperatively. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: This case series involved 13 patients with primary ACL injury who underwent anatomical double-bundle ACLR using hamstring tendon autograft between April 2012 and August 2013. All patients underwent preoperative quantitative MRI using a 3.0-T scanner with an 8-channel knee coil. Cartilage was divided into 18 compartments for compositional analysis, and average T1ρ values were calculated for each compartment. At the 10-year follow-up, 9 of the patients were available for patient-reported outcome (PRO) measures and radiographs. RESULTS: The 9 patients (6 female, 3 male) had a mean age of 26.4 years and a mean body mass index of 23.3 at surgery. All patients exhibited favorable PRO scores at the 10-year follow-up, but 5 patients showed osteoarthritis progression according to Kellgren-Lawrence (KL) grade. Although preoperative T1ρ values did not significantly correlate with PRO scores, patients with KL grade progression had significantly higher preoperative T1ρ values in the posterolateral tibial cartilage than those without progression (P = .04). CONCLUSION: Ten years after anatomical double-bundle ACLR, most patients reported favorable outcomes. Preoperative T1ρ values were not directly correlated with PROs, although the presence of a patient subset with progressive KL grades suggests that preoperative posterolateral tibial cartilage condition may influence long-term osteoarthritis progression.
  • Takuya Sakamoto, Shotaro Watanabe, Manato Horii, Ryu Ito, Seiji Kimura, Satoshi Yamaguchi, Seiji Ohtori, Takahisa Sasho
    Cureus 2024年9月30日  
  • Ryu Ito, Shotaro Watanabe, Takuya Sakamoto, Kaoru Toguchi, Manato Horii, Seiji Kimura, Satoshi Yamaguchi, Seiji Ohtori, Takahisa Sasho
    Cureus 2024年9月23日  
  • Kenta Kono, Satoshi Yamaguchi, Seiji Kimura, Yukio Mikami, Kaoru Kitsukawa, Koji Matsumoto, Mutsuaki Edama, Yuki Shiko, Manato Horii, Takahisa Sasho, Seiji Ohtori
    Skeletal radiology 2024年9月7日  
    OBJECTIVE: Knowledge of footprint anatomy is essential for ankle anterior talofibular ligament repair and reconstruction. We aimed to determine the intra- and inter-rater measurement reliability of the anterior talofibular ligament footprint dimension using three-dimensional MRI. METHODS: MRI images of 20 ankles with intact ligaments, including 11 with a single bundle and nine with double-bundle ligaments, were analyzed. Imaging was performed using a 3.0-Tesla MRI. Isotropic three-dimensional proton density-weighted images with a voxel size of 0.6 mm were obtained. The fibular and talar footprints were manually segmented using image processing software to create three-dimensional ligament footprints. The lengths, widths, and areas of each sample were measured. A certified orthopedic surgeon and a senior orthopedic fellow performed the measurements twice at 6-week intervals. The intra- and inter-rater differences in the measurements were calculated. RESULTS: The length, width, and area of the single-bundle fibular footprint were 8.7 mm, 5.4 mm, and 37.4 mm2, respectively. Those of the talar footprint were 8.4 mm, 4.3 mm, and 30.1 mm2, respectively. The inferior bundle of the double-bundle ligament was significantly smaller than the single and superior bundles (p < 0.001). No differences were observed between intra-rater measurements by either rater, with maximum differences of 0.7 mm, 0.5, and 1.7 mm2, in length, width, and area, respectively. The maximum inter-rater measurement differences were 1.9 mm, 0.5, and 2.4 mm2, respectively. CONCLUSION: Measurements of the anterior talofibular ligament dimensions using three-dimensional MRI were sufficiently reliable. This measurement method provides in vivo quantitative data on ligament footprint anatomy.
  • Yuriko Yoshimoto, Satoshi Yamaguchi, Seiji Kimura, Kaoru Kitsukawa, Koji Matsumoto, Yuki Shiko, Manato Horii, Shotaro Watanabe, Takahisa Sasho, Seiji Ohtori
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2024年8月19日  
    BACKGROUND: We aimed to evaluate the intra- and interrater measurement reliability of the lateral ankle ligament attachment locations using three-dimensional magnetic resonance imaging. METHODS: We analysed 54 participants with a mean age of 43 years who underwent three-dimensional ankle magnetic resonance imaging and had normal lateral ligaments. Bony landmarks of the distal fibula, talus, and calcaneus were identified in the reconstructed images. The centers of the anterior talofibular ligament and calcaneofibular ligament attachments were also identified. The distances between the landmarks and attachments were measured. Two raters performed the measurements twice, and intra- and interrater intraclass correlation coefficients were calculated. RESULTS: The intrarater intraclass correlation coefficient values were between 0.71 and 0.96 for the anterior talofibular ligament attachment measurements and between 0.77 and 0.95 for the calcaneofibular ligament attachments. The interrater intraclass correlation coefficient was higher than 0.7, except for the distance between the anterior talofibular ligament superior bundle and fibular obscure tubercle. The fibular attachment of a single-bundle anterior talofibular ligament was located 13.3 mm from the inferior tip and 43% along the anterior edge of the distal fibula. The superior and inferior bundles of the double-bundle ligament were located at 43% and 23%, respectively. The calcaneofibular ligament fibular attachment was 5.5 mm from the inferior tip, at 16% along the anterior edge of the distal fibula. CONCLUSION: The measurements of anterior talofibular ligament and calcaneofibular ligament attachment locations identified on three-dimensional magnetic resonance imaging were sufficiently reliable. This measurement method provides in vivo anatomical data on the lateral ankle ligament anatomy.

MISC

 114

書籍等出版物

 3

共同研究・競争的資金等の研究課題

 5