研究者業績

秋田 新介

Shinsuke Akita

基本情報

所属
千葉大学 医学部附属病院 形成美容外科 講師 (診療准教授)
(兼任)フロンティア医工学センター 講師
学位
博士(医学)(2013年3月 千葉大学)

J-GLOBAL ID
201901006965868309
researchmap会員ID
B000367861

Surgeon-scientistとして、形成外科学を、形態の異常や組織の変性にどこまで抗うことができるかを探求・挑戦する領域ととらえています。臨床医学の疑問を基礎研究に立ち戻って検証し、基礎研究で得られた知見を臨床医学に応用することを基本姿勢としています。現在は、特にリンパ管系を中心とした皮膚と皮下組織の変性、線維化、老化の理解と、その治療・再建にフォーカスしています。生物学的な手法と医工学的な手法を駆使し、病態の本質的な理解と、革新的な治療方法の開発や安全な治療マネージメント方法の確立を目指して研究に取り組んでいます。


学歴

 2

論文

 189
  • Saito Sakaguchi, Moe Tsutsumi, Shinsuke Akita, Masashi Konyo, Kentaro Kajiya
    Journal of Investigative Dermatology 2024年10月  
  • Hideki Tokumoto, Shinsuke Akita, Erina Yamamoto, Rikiya Nakamura, Shouko Hayama, Kentaro Kosaka, Yoshitaka Kubota, Nobuyuki Mitsukawa
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS 95 97-103 2024年8月  
    BACKGROUND: In microvascular breast reconstruction, the internal mammary vein (IMV) has emerged as the most common recipient vein. The open-Y technique can increase the vessel diameter via the bifurcation site. This study aimed to investigate the open-Y technique for IMV. METHODS: The characteristics and details of the operative procedure in patients who had undergone unilateral breast reconstruction with and without the open-Y approach for the free abdominal flap were compared. Differences in IMV anastomosis site (the bifurcation of the main duct or that of the perforator branch) were also compared in patients with the open-Y technique. The open-Y technique was performed on the IMV side. RESULTS: The open-Y and conventional groups included 127 and 62 patients, respectively. The main duct diameter of IMV was significantly smaller (median 2.5 vs. 3.0 mm, P < 0.001), and the rate of right-sided anastomosis (47.2 vs. 82.3%, P < 0.001) was significantly lower in the open-Y group. When comparing the main duct and perforator groups, the branch diameter (1.8 vs. 1.0 mm, P < 0.001) and the diameter after the open-Y technique (5.0 vs. 3.9 mm, P < 0.001) were significantly higher, and the angle of bifurcation (45° vs. 60°, P = 0.007) was significantly lower in the main duct group. CONCLUSIONS: Given a small venous diameter, the open-Y technique is superior, especially for left-sided breast reconstruction. Owing to the lower angle of bifurcation and large diameter, the open-Y technique at the main duct bifurcation of IMV causes less turbulence in the blood flow. TAKE HOME MESSAGE: The open-Y technique is especially effective for left-sided breast reconstruction. Considering the lower angle of bifurcation and large diameter, the open-Y technique at the main duct bifurcation of the internal mammary vein causes less turbulence in the blood flow.
  • Rika Hane, Shinsuke Akita, Yohei Kubo, Masahiro Takei, Nobuyuki Mitsukawa
    Plastic and reconstructive surgery. Global open 12(3) e5661 2024年3月  
    "COVID toe," one of the extrapulmonary disorders of coronavirus disease 2019 (COVID-19), may result in toe necrosis. In this case, we successfully reconstructed a severe COVID-19-induced defect in the great toe by using an innervated hemi-pulp V-Y advancement flap. A 48-year-old woman was diagnosed with fulminant myocarditis due to COVID-19 and received intensive care. Even after the acute phase, a skin defect measuring 10 mm × 7 mm was noted, exposing the underlying bone on her right great toe tip. Because of ulceration, she was unable to start walking training. To continue rehabilitation, we reconstructed it with the innerved hemi-pulp V-Y advancement flap. The pain improved quickly, and rehabilitation was resumed. During the 6-month follow-up period, no cosmetic or functional complications were observed. Plantar pressure measurements demonstrated favorable loading on the great toe, and it was a favorable outcome in walking function. This flap is a valuable option as one of the innervated flaps for toe-end necrosis with preserved blood flow, which helps in implementing prompt gait rehabilitation.
  • Kahoko Yamada, Shinsuke Akita, Nobuhiro Ando, Takeshi Tamura, Minoru Hayashi, Shiroh Isono, Nobuyuki Mitsukawa
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2024年1月19日  
    The purpose of this study was to evaluate changes in mandibular position during midface distraction. Midface distraction was performed in patients with syndromic craniosynostosis to increase upper airway volume. Although this treatment resulted in changes in occlusion, the concomitant changes in mandibular position were poorly understood. In this retrospective study, three-dimensional (3D) cephalograms were obtained before and after midface distraction in 15 patients with syndromic craniosynostosis. Perioperative polysomnography scores and changes in maxillary and mandibular position, mandibular volume, and upper airway volume were analyzed. Results showed a significant improvement in apnea-hypopnea index (AHI) (from 20.6 ± 21.3 to 6.9 ± 5.1, p < 0.05) and upper airway volume (from 2951.65 ± 2286.38 to 5218.04 ± 3150.05 mm3, p < 0.001). When the lowest point of the sella turcica was set as the reference point, the mandible moved significantly in an anterior direction (from 47.9 ± 11.5 to 51.9 ± 9.8 mm, p < 0.05). Mandibular volume did not change significantly perioperatively (from 32530.19 ± 10726.01 to 35590.50 ± 14879.21 mm3, p = 0.10). There were positive correlations between the rates of improvement in AHI and the amount of mandibular movement in the anterior and inferior directions (both p < 0.05). Within the limitations of the study, it seems that the mandible moved in the anterior-inferior direction after midface distraction, and the amount of movement correlated with improvement in respiratory function. Therefore, it is important to consider the position of the mandible when determining the direction of midface distraction, as it may influence the therapeutic effect.
  • Isnan Nur Rifai, Prima Asmara Sejati, Shinsuke Akita, Masahiro Takei
    IEEE Transactions on Instrumentation and Measurement 2024年  

MISC

 294

講演・口頭発表等

 139

共同研究・競争的資金等の研究課題

 20

社会貢献活動

 12