西城忍

研究者氏名	西城忍

URL
所属	千葉大学
部署	真菌医学研究センター
職名
J-Global ID	202001017026038525

研究分野

ライフサイエンス / 免疫学 /

論文

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Involvement of Dectin-2 in the innate inflammatory response triggered by influenza virus hemagglutinin

Hideki Yamamoto Chikako Tomiyama Sho Yamasaki Shinobu Saijo Yoichiro Iwakura Kazuyoshi Kawakami

Advances in Infectious Diseases 13(3) 478-497 2023年9月 [査読有り]

Dectin-1/IL-15 Pathway Affords Protection against Extrapulmonary <i>Aspergillus fumigatus</i> Infection by Regulating Natural Killer Cell Survival

Fábio S.Y. Yoshikawa Maki Wakatsuki Kosuke Yoshida Rikio Yabe Shota Torigoe Sho Yamasaki Glen N. Barber Shinobu Saijo

Journal of Innate Immunity 1-15 2023年1月

<i>Aspergillus fumigatus</i> is a ubiquitous, yet potentially pathogenic, mold. The immune system employs innate receptors, such as dectin-1, to recognize fungal pathogens, but the immunological networks that afford protection are poor...

Epidermal clearance of Candida albicans is mediated by IL-17 but independent of fungal innate immune receptors

Mari T Iwasawa Hideaki Miyachi Seiichiro Wakabayashi Takashi Sugihira Reika Aoyama Seitaro Nakagawa Yuki Katayama Mitsutoshi Yoneyama Hiromitsu Hara Yoichiro Iwakura Masanori Matsumoto Naohiro Inohara Hanako Koguchi-Yoshioka Manabu Fujimoto Gabriel Núñez Hiroyuki Matsue Yuumi Nakamura Shinobu Saijo

International Immunology 34(8) 409-420 2022年5月

Abstract

IL-17 plays important roles in host defense against Candida albicans at barrier surfaces and during invasive infection. However, the role of IL-17 in host defense after colonization of the epidermis, a main site of C. albicans infection...

The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17.

Yulia Makusheva Soo-Hyun Chung Aoi Akitsu Natsumi Maeda Takumi Maruhashi Xiao-Qi Ye Tomonori Kaifu Shinobu Saijo Haiyang Sun Wei Han Ce Tang Yoichiro Iwakura

Experimental animals 2022年2月

Clec1A, a member of C-type lectin receptor family, has a carbohydrate recognition domain in its extracellular region, but no known signaling motif in the cytoplasmic domain. Clec1a is highly expressed in endothelial cells and weakly in dendritic c...

TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens

Rikio Yabe Soo-Hyun Chung Masanori A. Murayama Sachiko Kubo Kenji Shimizu Yukiko Akahori Takumi Maruhashi Akimasa Seno Tomonori Kaifu Shinobu Saijo Yoichiro Iwakura

Nature Communications 12(1) 2021年12月

<title>Abstract</title>TARM1 is a member of the leukocyte immunoglobulin-like receptor family and stimulates macrophages and neutrophils in vitro by associating with FcRγ. However, the function of this molecule in the regulation of the immune syst...