中司寛子

研究者氏名	中司寛子

URL
所属	千葉大学
部署	大学院薬学研究院免疫微生物学研究室
職名	准教授
学位	博士（薬学）(東京理科大学)
J-Global ID	201901001414684418

研究分野

ライフサイエンス / 免疫学 /

経歴

2023年8月

現在

文部科学省研究振興局学術調査官

2022年4月

現在

千葉大学大学院薬学研究院免疫微生物学研究室准教授

2017年7月

2022年3月

慶應義塾大学医学部微生物学・免疫学教室助教

2014年4月

2017年6月

慶應義塾大学医学部微生物学・免疫学教室特任助教

2011年4月

2014年5月

National Institute of Dental and Craniofacial Research, National Institutes of Health (USA) Visiting Fellow

論文

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Prevention of experimental autoimmune encephalomyelitis by targeting 6-sulfo sialyl Lewis X glycans involved in lymphocyte homing

Qianqian Liu Wei Xiong Sachiyo Obara Hirohito Abo Hiroko Nakatsukasa Hiroto Kawashima

International Immunology 2024年2月

Abstract

Lymphocyte homing to peripheral lymph nodes (PLN) is critical for immune surveillance. However, autoimmune diseases such as multiple sclerosis (MS) can occur due to excessive immune responses in the PLN. Here we show that 6-sulfo sialyl...

Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation.

Sang-A Park Yun-Ji Lim Wai Lim Ku Dunfang Zhang Kairong Cui Liu-Ya Tang Cheryl Chia Peter Zanvit Zuojia Chen Wenwen Jin Dandan Wang Junji Xu Ousheng Liu Fu Wang Alexander Cain Nancy Guo Hiroko Nakatsukasa Chuan Wu Ying E Zhang Keji Zhao WanJun Chen

Nature communications 13(1) 6069-6069 2022年10月

Interleukin-9 (IL-9)-producing CD4+ T helper cells (Th9) have been implicated in allergy/asthma and anti-tumor immunity, yet molecular insights on their differentiation from activated T cells, driven by IL-4 and transforming growth factor-beta (TG...

STAP-2 Is a Novel Positive Regulator of TCR-Proximal Signals.

Kodai Saitoh Jun-Ichi Kashiwakura Kota Kagohashi Yuto Sasaki Shoya Kawahara Yuichi Sekine Yuichi Kitai Ryuta Muromoto Michiko Ichii Hiroko Nakatsukasa Akihiko Yoshimura Kenji Oritani Tadashi Matsuda

Journal of immunology (Baltimore, Md. : 1950) 209(1) 57-68 2022年7月 [査読有り]

TCR ligation with an Ag presented on MHC molecules promotes T cell activation, leading to the selection, differentiation, and proliferation of T cells and cytokine production. These immunological events are optimally arranged to provide appropriat...

Editorial: Hexose Uptake and Metabolism in Immune Homeostasis and Inflammation.

Dunfang Zhang Chaohong Liu Hiroko Nakatsukasa WanJun Chen

Frontiers in immunology 12 832293-832293 2022年1月

Single-Cell Analysis Revealed the Role of CD8+ Effector T Cells in Preventing Cardioprotective Macrophage Differentiation in the Early Phase of Heart Failure.

Kyoko Komai Minako Ito Seitaro Nomura Shigeyuki Shichino Manami Katoh Shintaro Yamada Toshiyuki Ko Mana Iizuka-Koga Hiroko Nakatsukasa Akihiko Yoshimura

Frontiers in immunology 12 763647-763647 2021年10月 [査読有り]

Heart failure is a complex clinical syndrome characterized by insufficient cardiac function. Heart-resident and infiltrated macrophages have been shown to play important roles in the cardiac remodeling that occurs in response to cardiac pressure o...