Shunsuke Ishii   Haruka Chino   Koji L. Ode   Yoshitaka Kurikawa   Hiroki R. Ueda   Akira Matsuura   Noboru Mizushima   Eisuke Itakura   
Molecular Biology of the Cell 2023年2月 [査読有り]
The endoplasmic reticulum (ER) is a major cell compartment where protein synthesis, folding and post-translational modifications occur with assistance from a wide variety of chaperones and enzymes. Quality control systems selectively eliminate abn...
Yuki Date   Akira Matsuura   Eisuke Itakura   
Cell Death Discovery 8(1) 37-37 2022年12月 [査読有り]
Abstract
Autophagy plays important role in the intracellular protein quality control system by degrading abnormal organelles and proteins, including large protein complexes such as ribosomes. The eukaryotic chaperonin tailless complex polypeptide...
Endocytic internalization of extracellular proteins plays roles in signaling, nutrient uptake, immunity, and extracellular protein quality control. However, there are few protocols for analyzing the lysosomal degradation of extracellular protein. ...