Proceedings of the National Academy of Sciences of the United States of America 120(49) e2302903120 2023年12月 [査読有り]
Uncontrolled type 2 immunity by type 2 helper T (Th2) cells causes intractable allergic diseases; however, whether the interaction of CD4+ T cells shapes the pathophysiology of allergic diseases remains unclear. We identified a subset of Th2 cells...
Tissue-resident memory T cells (TRM cells) are crucial mediators of adaptive immunity in nonlymphoid tissues. However, the functional heterogeneity and pathogenic roles of CD4+ TRM cells that reside within chronic inflammatory lesions remain unkno...
Jin Kumagai   Kiyoshi Hirahara   Toshinori Nakayama   
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 39(2) 114-23 2016年 [査読有り]
CD4(+) T cells play central roles to appropriate protection against pathogens. While, they can also be pathogenic driving inflammatory diseases. Besides the classical model of differentiation of T helper 1 (Th1) and Th2 cells, various CD4(+) T cel...
Internal medicine (Tokyo, Japan) 52(22) 2573-6 2013年 [査読有り]
A 74-year-old woman visited an otolaryngology clinic with pharyngeal pain, and was diagnosed with a peritonsillar abscess. She received antibiotics and underwent incisional drainage, but displayed high white blood cell and blast cell counts, and w...