大学院医学研究院

研究分野

ライフサイエンス / 腫瘍生物学 / ピロリ菌胃癌
ライフサイエンス / 進化生物学 / メチローム進化

論文

Chromatin activation with H3K36me2 and compartment shift in metastatic castration-resistant prostate cancer

Sanji Kanaoka Atsushi Okabe Manato Kanesaka Bahityar Rahmutulla Masaki Fukuyo Motoaki Seki Takayuki Hoshii Hiroaki Sato Yusuke Imamura Shinichi Sakamoto Tomohiko Ichikawa Atsushi Kaneda

Cancer Letters 588 216815-216815 2024年4月

Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma

Harue Mizokami Atsushi Okabe Ruchi Choudhary Masato Mima Kenta Saeda Masaki Fukuyo Bahityar Rahmutulla Motoaki Seki Boon-Cher Goh Satoru Kondo Hirotomo Dochi Makiko Moriyama-Kita Kiyoshi Misawa Toyoyuki Hanazawa Patrick Tan Tomokazu Yoshizaki Melissa Jane Fullwood Atsushi Kaneda

eBioMedicine 102 105057-105057 2024年4月

Genomic Analysis of Undifferentiated Carcinoma of the Pancreas with Squamous Differentiation: A Case Report.

Motoyasu Kan Yusuke Kouchi Hiroshi Ohyama Genki Usui Masaki Fukuyo Shigetsugu Takano Takashi Kishimoto Atsushi Kaneda Masayuki Ohtsuka Naoya Kato

Cureus 16(2) e55175 2024年2月

Pancreatic cancer is an intractable malignancy associated with a dismal prognosis. Undifferentiated carcinoma, a rare subtype, poses a clinical challenge owing to a limited understanding of its molecular characteristics. In this study, we conducte...

Genome-wide analysis of DNA methylation in pseudomyxoma peritonei originated from appendiceal neoplasms.

Kiyoko Takane Tingwei Cai Rei Noguchi Yoshimasa Gohda Tsuneo Ikenoue Kiyoshi Yamaguchi Yasunori Ota Tomomichi Kiyomatsu Hideaki Yano Masaki Fukuyo Motoaki Seki Rahmutulla Bahityar Atsushi Kaneda Yoichi Furukawa

Oncology 2024年1月

INTRODUCTION: Pseudomyxoma peritonei (PMP) is a disease characterized by progressive accumulation of intraperitoneal mucinous ascites produced by neoplasms in the abdominal cavity. Since the prognosis of patients with PMP remain unsatisfactory, th...

The Link of mRNA and rRNA Transcription by PUF60/FIR through TFIIH/P62 as a Novel Therapeutic Target for Cancer.

Kouichi Kitamura Tyuji Hoshino Atsushi Okabe Masaki Fukuyo Bahityar Rahmutulla Nobuko Tanaka Sohei Kobayashi Tomoaki Tanaka Takashi Shida Mashiro Ueda Toshinari Minamoto Hisahiro Matsubara Atsushi Kaneda Hideshi Ishii Kazuyuki Matsushita

International journal of molecular sciences 24(24) 2023年12月

The interaction between mRNA and ribosomal RNA (rRNA) transcription in cancer remains unclear. RNAP I and II possess a common N-terminal tail (NTT), RNA polymerase subunit RPB6, which interacts with P62 of transcription factor (TF) IIH, and is a c...