Arthritis Research & Therapy 24(1) 2022年12月 [査読有り]
Abstract
Objectives
Methotrexate (MTX) is an anchor drug for the treatment of rheumatoid arthritis (RA). However, the precise mechanisms by which MTX stalls RA progression and alleviates the ensuing disease effects remain unknown. The aim of t...
Xianyong Yin Kwangwoo Kim Hiroyuki Suetsugu So-Young Bang Leilei Wen Masaru Koido Eunji Ha Lu Liu Yuma Sakamoto Sungsin Jo Rui-Xue Leng Nao Otomo Young-Chang Kwon Yujun Sheng Nobuhiko Sugano Mi Yeong Hwang Weiran Li Masaya Mukai Kyungheon Yoon Minglong Cai Kazuyoshi Ishigaki Won Tae Chung He Huang Daisuke Takahashi Shin-Seok Lee Mengwei Wang Kohei Karino Seung-Cheol Shim Xiaodong Zheng Tomoya Miyamura Young Mo Kang Dongqing Ye Junichi Nakamura Chang-Hee Suh Yuanjia Tang Goro Motomura Yong-Beom Park Huihua Ding Takeshi Kuroda Jung-Yoon Choe Chengxu Li Hiroaki Niiro Youngho Park Changbing Shen Takeshi Miyamoto Ga-Young Ahn Wenmin Fei Tsutomu Takeuchi Jung-Min Shin Keke Li Yasushi Kawaguchi Yeon-Kyung Lee Yong-Fei Wang Koichi Amano Dae Jin Park Wanling Yang Yoshifumi Tada Yu Lung Lau Ken Yamaji Zhengwei Zhu Masato Shimizu Takashi Atsumi Akari Suzuki Takayuki Sumida Yukinori Okada Koichi Matsuda Keitaro Matsuo Yuta Kochi Kazuhiko Yamamoto Koichiro Ohmura Tae-Hwan Kim Sen Yang Takuaki Yamamoto Bong-Jo Kim Nan Shen Shiro Ikegawa Hye-Soon Lee Xuejun Zhang Chikashi Terao Yong Cui Sang-Cheol Bae
Annals of the rheumatic diseases 81(9) 1273-80 2022年5月 [査読有り]
OBJECTIVE: Genome-wide association studies (GWAS) have identified >100 risk loci for systemic lupus erythematosus (SLE), but the disease genes at most loci remain unclear, hampering translation of these genetic discoveries. We aimed to prioritise ...
Hiroyuki Suetsugu Kwangwoo Kim Takuaki Yamamoto So-Young Bang Yuma Sakamoto Jung-Min Shin Nobuhiko Sugano Ji Soong Kim Masaya Mukai Yeon-Kyung Lee Koichiro Ohmura Dae Jin Park Daisuke Takahashi Ga-Young Ahn Kohei Karino Young-Chang Kwon Tomoya Miyamura Jihye Kim Junichi Nakamura Goro Motomura Takeshi Kuroda Hiroaki Niiro Takeshi Miyamoto Tsutomu Takeuchi Katsunori Ikari Koichi Amano Yoshifumi Tada Ken Yamaji Masato Shimizu Takashi Atsumi Taisuke Seki Yoshiya Tanaka Toshikazu Kubo Ryo Hisada Tomokazu Yoshioka Mihoko Yamazaki Tamon Kabata Tomomichi Kajino Yoichi Ohta Takahiro Okawa Yohei Naito Ayumi Kaneuji Yuji Yasunaga Kenji Ohzono Kohei Tomizuka Masaru Koido Koichi Matsuda Yukinori Okada Akari Suzuki Bong-Jo Kim Yuta Kochi Hye-Soon Lee Shiro Ikegawa Sang-Cheol Bae Chikashi Terao
Human Molecular Genetics 31(7) 1082-1095 2021年12月 [査読有り]
<title>Abstract</title>
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<title>Introduction</title>
Osteonecrosis of the femoral head (ONFH) involves necrosis of bone and bone marrow of the femoral head caused by ischemia with unknown etiology. Previous genetic studies on ONFH failed t...
Journal of Orthopaedic Science 26(1) 46-68 2021年1月 [査読有り]
Purpose: The Clinical Practice Guidelines for Osteonecrosis of the Femoral Head (ONFH) 2019 Edition, written by the working group for ONFH guidelines of the Japanese Investigation Committee (JIC) for ONFH under the auspices of the Japanese Ministr...
Xianyong Yin Kwangwoo Kim Hiroyuki Suetsugu So-Young Bang Leilei Wen Masaru Koido Eunji Ha Lu Liu Yuma Sakamoto Sungsin Jo Rui-Xue Leng Nao Otomo Viktoryia Laurynenka Young-Chang Kwon Yujun Sheng Nobuhiko Sugano Mi Yeong Hwang Weiran Li Masaya Mukai Kyungheon Yoon Minglong Cai Kazuyoshi Ishigaki Won Tae Chung He Huang Daisuke Takahashi Shin-Seok Lee Mengwei Wang Kohei Karino Seung-Cheol Shim Xiaodong Zheng Tomoya Miyamura Young Mo Kang Dongqing Ye Junichi Nakamura Chang-Hee Suh Yuanjia Tang Goro Motomura Yong-Beom Park Huihua Ding Takeshi Kuroda Jung-Yoon Choe Chengxu Li Hiroaki Niiro Youngho Park Changbing Shen Takeshi Miyamoto Ga-Young Ahn Wenmin Fei Tsutomu Takeuchi Jung-Min Shin Keke Li Yasushi Kawaguchi Yeon-Kyung Lee Yongfei Wang Koichi Amano Dae Jin Park Wanling Yang Yoshifumi Tada Ken Yamaji Masato Shimizu Takashi Atsumi Akari Suzuki Takayuki Sumida Yukinori Okada Koichi Matsuda Keitaro Matsuo Yuta Kochi Leah C Kottyan Matthew T Weirauch Sreeja Parameswaran Shruti Eswar Hanan Salim Xiaoting Chen Kazuhiko Yamamoto John B Harley Koichiro Ohmura Tae-Hwan Kim Sen Yang Takuaki Yamamoto Bong-Jo Kim Nan Shen Shiro Ikegawa Hye-Soon Lee Xuejun Zhang Chikashi Terao Yong Cui Sang-Cheol Bae
Annals of the rheumatic diseases 80(5) 632-640 2020年12月 [査読有り]
OBJECTIVE: Systemic lupus erythematosus (SLE), an autoimmune disorder, has been associated with nearly 100 susceptibility loci. Nevertheless, these loci only partially explain SLE heritability and their putative causal variants are rarely prioriti...
大学院国際学術研究院