JOURNAL OF BIOMEDICAL OPTICS 14(5) 054017 2009年9月 [査読有り]
Animal imaging sources have become an indispensable material for biological sciences. Specifically, gene-encoded biological probes serve as stable and high-performance tools to visualize cellular fate in living animals. We use a somatic cell cloni...
Nomoto, T Okada, T Shimazaki, K Yoshioka, T Nonaka-Sarukawa, M Ito, T Takeuchi, K Katsura, K.I Mizukami, H Kume, A Ookawara, S Ikeda, U Katayama, Y Ozawa, K
YH Liu T Okada K Sheykholeslami K Shimazaki T Nomoto SI Muramatsu T Kanazawa K Takeuchi R Ajalli H Mizukami A Kume K Ichimura K Ozawa
MOLECULAR THERAPY 12(4) 725-733 2005年10月 [査読有り]
Recombinant adeno-associated virus (AAV) vectors are of interest for cochlear gene therapy because of their ability to mediate the efficient transfer and long-term stable expression of therapeutic genes in a wide variety of postmitotic tissues wit...
Background. The characteristics of adenovirus-mediated gene transfer into the kidney are not well examined. We studied the effects of contact time and temperature on adenovirus-mediated transgene expression in rat kidneys, using catheter-based in ...
Rodent and human clinical studies have shown that transplantation of bone marrow stem cells to the ischemic myocardium results in improved cardiac function. In this study, cynomolgus monkey acute myocardial infarction was generated by ligating the...
T Nomoto T Okada K Shimazaki T Yoshioka M Sarukawa K Takeuchi H Mizukami T Matsushita K Katsura K Yamamoto A Kume U Ikeda S Ookawara Y Katayama K Ozawa
Background/Aim: Gene transfer into the kidney has great potential as a novel therapeutic approach. However, an efficient method of gene transfer into the kidney has not been established. We explored the transduction efficiency of renal cells in vi...
大学院国際学術研究院