花岡英紀

研究者氏名	花岡英紀
	ハナオカヒデキ
URL	https://www.ho.chiba-u.ac.jp/crc/index.html
所属	千葉大学
部署	医学部附属病院臨床試験部
職名
学位	医学博士
その他の所属	大学院　医学研究院　臨床研究・治療評価学
J-Global ID	200901035775313850

研究キーワード

レギュラトリーサイエンス

研究分野

その他 / その他 /

経歴

2013年9月

現在

千葉大学医学部附属病院臨床試験部教授臨床試験部長

2013年9月

現在

千葉大学大学院医学研究院臨床研究・医療評価学教授

2008年

2013年

千葉大学医学部附属病院臨床試験部講師臨床試験部長

2003年

2008年

千葉大学医学部附属病院治験管理・支援センター助手

論文

A Phase Ib Study of Durvalumab (MEDI4736) in Combination with Carbon-Ion Radiotherapy and Weekly Cisplatin for Patients with Locally Advanced Cervical Cancer (DECISION Study): The Early Safety and Efficacy Results.

Noriyuki Okonogi Kazutoshi Murata Shigeru Yamada Yuji Habu Makoto Hori Tomoya Kurokawa Yosuke Inaba Tadami Fujiwara Yasuhisa Fujii Michiko Hanawa Yohei Kawasaki Yoko Hattori Kazuko Suzuki Kyoko Tsuyuki Masaru Wakatsuki Masashi Koto Sumitaka Hasegawa Hitoshi Ishikawa Hideki Hanaoka Makio Shozu Hiroshi Tsuji Hirokazu Usui

International journal of molecular sciences 24(13) 2023年6月

We conducted a phase Ib study to examine the safety of a combination of carbon-ion RT (CIRT) with durvalumab (MEDI4736; AstraZeneca) in patients with locally advanced cervical cancer. This was an open-label, single-arm study with a modified 3 + 3 ...

A Multicenter Randomized Controlled Trial To Evaluate the Efficacy and Safety of Nelfinavir in Patients with Mild COVID-19

Taiga Miyazaki Naoki Hosogaya Yuri Fukushige Sachiko Takemori Shinpei Morimoto Hiroshi Yamamoto Makoto Hori Yoshihito Ozawa Yuki Shiko Yosuke Inaba Tomoya Kurokawa Hideki Hanaoka Shoya Iwanami Kwangsu Kim Shingo Iwami Koichi Watashi Ken Miyazawa Takashi Umeyama Satoshi Yamagoe Yoshitsugu Miyazaki Takaji Wakita Makoto Sumiyoshi Tatsuro Hirayama Koichi Izumikawa Katsunori Yanagihara Hiroshi Mukae Hitoshi Kawasuji Yoshihiro Yamamoto Norihito Tarumoto Hiroshi Ishii Hideaki Ohno Kazuhiro Yatera Hiroshi Kakeya Yoshiko Kichikawa Yasuyuki Kato Tetsuya Matsumoto Makoto Saito Hiroshi Yotsuyanagi Shigeru Kohno

Microbiology Spectrum 2023年5月

The anti-HIV drug nelfinavir suppresses the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro . However, its efficacy in patients with COVID-19 has not been studied.

Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial.

Misuzu Fujita Kengo Nagashima Minobu Shimazu Misae Suzuki Ichiro Tauchi Miwa Sakuma Setsuko Yamamoto Hideki Hanaoka Makio Shozu Nobuhide Tsuruoka Tokuzo Kasai Akira Hata

PloS one 18(6) e0286909 2023年

PURPOSE: In terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise s...

Exploratory clinical trial to evaluate the efficacy and safety of transdermal electrical stimulation in patients with central retinal artery occlusion.

Gen Miura Tadami Fujiwara Takayuki Iwase Yoshihito Ozawa Yuki Shiko Yohei Kawasaki Tomohiro Nizawa Tomoaki Tatsumi Takayuki Baba Takuji Kurimoto Sotaro Mori Makoto Nakamura Hideki Hanaoka Shuichi Yamamoto

PloS one 18(2) e0282003 2023年

PURPOSE: To evaluate the efficacy and safety of transdermal electrical stimulation (TdES) using skin electrodes in patients with central retinal artery occlusion (CRAO). METHODS: Five eyes of five patients with CRAO underwent TdES (10-ms biphasic ...

Germline variants of IGHV3-53 / V3-66 are determinants of antibody responses to the BNT162b2 mRNA COVID-19 vaccine.

Yoichi Mashimo Keiko Yamazaki Takahiro Kageyama Shigeru Tanaka Toshibumi Taniguchi Kazuyuki Matsushita Hidetoshi Igari Hideki Hanaoka Koutaro Yokote Hiroshi Nakajima Yoshihiro Onouchi

The Journal of infection 85(6) 702-769 2022年11月

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MISC

Phase I study of a new concept cancer vaccine composed artificial intelligence (AI)-designed shared-antigen peptides plus combined synergistically activating antigen-specific CTL reaction (CYT001) in patients with advanced hepatocellular carcinoma (CRESCENT 1)

Sadahisa Ogasawara Hiroaki Kanzaki Keisuke Koroki Kengo Kanayama Susumu Maruta Kazufumi Kobayashi Souichiro Kiyono Masato Nakamura Naoya Kanogawa Takayuki Kondo Eiichiro Suzuki Yoshihiko Ooka Shingo Nakamoto Akinobu Tawada Tetsuhiro Chiba Makoto Arai Hiroyuki Nakada Nobuko Yamaguchi Hideki Hanaoka Naoya Kato

JOURNAL OF CLINICAL ONCOLOGY 38(4) 2020年2月

膠原病における免疫抑制薬の適応と使い方関節リウマチとトファシチニブ

古田俊介花岡英紀

月刊リウマチ科 51(1) 83-88 2014年1月 [招待有り]

Centralization of reviews by IRBs in University Hospitals: Consideration of collaborative IRB in University Hospital Clinical Trial Alliance

Kazuhiko Matsumoto Yoshihiro Arakawa Ryuji Koike Tetsuya Nakamura Hideki Hanaoka Masato Honma Hirohisa Yoshizawa

Japanese Journal of Clinical Pharmacology and Therapeutics 44(3) 207-215 2013年5月

The University Hospital Clinical Trial Alliance (UHCT Alliance) was established in 2006 with the goal to conduct global studies in Japan, and is presently organized by 7 national university hospitals in the Kanto and Shin-Etsu area To promote more...

A randomized, open-label trial comparing the efficacy and safety of pitavastatin with atorvastatin in Japanese patients with hypercholesterolemia.

Koutaro Yokote Hideaki Bujo Hideki Hanaoka Masaki Shinomiya Keiji Mikami Kohji Shirai Tetsuo Nishikawa Tatsuhiko Kodama Norio Tada Yasushi Saito

DIABETES 56 A233-A233 2007年6月

最近の糖尿病治療薬を中心とした医薬品の承認申請について

花岡英紀粟屋智一平山佳伸藤原康弘

糖尿病合併症 17(1) 2003年

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