Yasushi Yoshida Hidetoshi Ida Takashi Mino Masami Sakamoto
Molecules 28(11) 2023年6月
1,2,4-Triazole and 1,2,4-triazoline are important components of bioactive molecules and catalysts employed in organic synthesis. Therefore, the efficient synthesis of these components has received significant research attention. However, studies o...
Takashi Mino Kaho Takaya Kaito Koki Natsume Akimoto Yasushi Yoshida Yoshio Kasashima Masami Sakamoto
Organic and Biomolecular Chemistry 2023年
We synthesized N-alkyl-N-cinnamoyl amide type phosphine-olefin compounds 1 and found axial chirality in a C(aryl)-N(amide) bond in compounds 1 by HPLC analysis using a chiral stationary phase column. We successfully obtained enantiomeric isomers o...
Takashi Mino Kaho Takaya Kaito Koki Natsume Akimoto Yasushi Yoshida Yoshio Kasashima Masami Sakamoto
Organic & Biomolecular Chemistry 21(13) 2775-2778 2023年
We synthesized cinnamoyl amide type compounds 1 with axial chirality. We demonstrated the use of (–)-1 for chiral ligands in Pd-catalyzed asymmetric allylic substitution reactions of allylic esters with indoles (up to 97% ee).
大学院国際学術研究院