田中繁

研究者氏名	田中繁
	タナカシゲル
URL	http://www.m.chiba-u.jp/class/allergy/
所属	千葉大学
部署	医学部附属病院
職名
学位	医学博士(千葉大学)
J-Global ID	201801020069044700

研究キーワード

制御性T細胞 ,ヘルパーT細胞 ,膠原病 ,関節リウマチ

研究分野

ライフサイエンス / 免疫学 /
ライフサイエンス / 膠原病、アレルギー内科学 /

経歴

2018年3月

現在

千葉大学医学部附属病院アレルギー・膠原病内科助教

2015年10月

2018年2月

Benaroya Research Institute

2010年4月

2015年9月

千葉大学医学部附属病院

2009年4月

2010年3月

千葉県済生会習志野病院

2006年4月

2009年3月

旭中央病院

論文

12 3 4 5 >

Physiological and immunological barriers in the lung

Takahiro Kageyama Takashi Ito Shigeru Tanaka Hiroshi Nakajima

Seminars in Immunopathology 2024年3月 [査読有り][招待有り]

Abstract

The lungs serve as the primary organ for respiration, facilitating the vital exchange of gases with the bloodstream. Given their perpetual exposure to external particulates and pathogens, they possess intricate protective barriers. Cellu...

Single-cell RNA sequencing of submandibular gland reveals collagen type XV-positive fibroblasts as a disease-characterizing cell population of IgG4-related disease.

Shigeru Tanaka Takuya Yamamoto Arifumi Iwata Masahiro Kiuchi Kota Kokubo Tomohisa Iinuma Takahiro Sugiyama Toyoyuki Hanazawa Kiyoshi Hirahara Kei Ikeda Hiroshi Nakajima

Arthritis research & therapy 26(1) 55-55 2024年2月

OBJECTIVES: IgG4-related disease (IgG4-RD) is a systemic autoimmune disease with an unknown etiology, affecting single/multiple organ(s). Pathological findings include the infiltration of IgG4-producing plasma cells, obliterative phlebitis, and st...

Eosinophils Contribute to Oral Tolerance via Induction of RORγt-Positive Antigen-Presenting Cells and RORγt-Positive Regulatory T Cells

Shunjiro Kurihara Kotaro Suzuki Masaya Yokota Takashi Ito Yuki Hayashi Ryo Kikuchi Takahiro Kageyama Kazuyuki Meguro Shigeru Tanaka Arifumi Iwata Yoshiyuki Goto Akira Suto Hiroshi Nakajima

Biomolecules 14(1) 89-89 2024年1月 [査読有り]

IL-21 is required for the maintenance and pathogenesis of murine Vγ4+ IL-17-producing γδT cells

Junichi Ishikawa Akira Suto Kazuya Abe Yuki Hayashi Kensuke Suga Shigeru Tanaka Takahiro Kageyama Arifumi Iwata Kazumasa Suzuki Kotaro Suzuki Hiroshi Nakajima

Frontiers in Immunology 14 2023年8月

Murine IL-17-producing γδT (γδT17) cells are divided into two subsets: natural γδT17 (nγδT17) cells, whose development is restricted to the fetal thymus, and inducible γδT17 cells, which require antigen exposure for their IL-17 production and are ...

CCR4 predicts the efficacy of abatacept in rheumatoid arthritis patients through the estimation of Th17 and Treg cell abundance.

Shigeru Tanaka Keishi Etori Koto Hattori Jun Tamura Kei Ikeda Takahiro Kageyama Kazuyuki Meguro Taro Iwamoto Arifumi Iwata Shunsuke Furuta Akira Suto Kotaro Suzuki Hiroshi Nakajima

Modern rheumatology 2023年7月

OBJECTIVE: Predicting the efficacy of biological disease-modifying anti-rhematic drugs (bDMARDs) is challenging. In this study, we aimed to explore markers that predict the efficacy of abatacept in rheumatoid arthritis (RA) patients. METHODS: Thir...