Xiayun Wan Akifumi Eguchi Akemi Sakamoto Yuko Fujita Yong Yang Youge Qu Masahiko Hatano Chisato Mori Kenji Hashimoto
Brain, behavior, & immunity - health 27 100573-100573 2023年2月
The spleen is a key immune-related organ that plays a role in communication between the brain and the immune system through the brain-spleen axis and brain-gut-microbiota axis. However, how the gut microbiota affects spleen and brain function rema...
Yong Yang Akifumi Eguchi Xiayun Wan Lijia Chang Xingming Wang Youge Qu Chisato Mori Kenji Hashimoto
Progress in neuro-psychopharmacology & biological psychiatry 120 110652-110652 2023年1月
The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7) is known to regulate the cholinergic ascending anti-inflammatory pathway. We previously reported that Chrna7 knock-out (KO) mice show depression-like behaviors thro...
Kodai Motohira Yared Beyene Yohannes Yoshinori Ikenaka Akifumi Eguchi Shouta Mm Nakayama Victor Wepener Nico J Smit Johan Hj VAN Vuren Mayumi Ishizuka
The Journal of veterinary medical science 2023年1月
Dichlorodiphenyltrichloroethane (DDT) is an organochlorine insecticide used worldwide. Several studies have reported the toxic effects of DDT and its metabolites on steroid hormone biosynthesis; however, its environmental effects are not well unde...
Youge Qu Akifumi Eguchi Xiayun Wan Li Ma Lijia Chang Jiajing Shan Yong Yang Chisato Mori Kenji Hashimoto
Psychiatry research 320 115020-115020 2022年12月
3,4-Methylenedioxymethamphetamine (MDMA), the most widely used illicit compound worldwide, is the most attractive therapeutic drug for post-traumatic stress disorder (PTSD). Recent observational studies of US adults demonstrated that lifetime MDMA...
Xingming Wang Akifumi Eguchi Yong Yang Lijia Chang Xiayun Wan Jiajing Shan Youge Qu Li Ma Chisato Mori Jianjun Yang Kenji Hashimoto
Neurobiology of disease 176 105951-105951 2022年12月
Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central nervous system. Dietary intake of cuprizone (CPZ) produces demyelination resembling that of patients with MS. Given the role of the vagus nerve in gut-microb...
大学院国際学術研究院