高屋明子

研究者氏名	高屋明子
	タカヤアキコ
URL
所属	千葉大学
部署	大学院薬学研究院分子医薬科学　薬学部
職名	准教授
学位	博士（薬学）(千葉大学)
J-Global ID	200901050165331457

研究キーワード

シャペロン・プロテアーゼ ,薬剤耐性 ,細菌感染症

研究分野

ライフサイエンス / 細菌学 /

受賞

平成18年黒屋奨学賞

論文

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Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA

Junpei Yamaguchi Teruhisa Manome Yasumasa Hara Yuriko Yamazaki Yuumi Nakamura Masami Ishibashi Akiko Takaya

Frontiers in Pharmacology 15 2024年4月

The virulence of Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), depends on the expression of toxins and virulence factors controlled by the quorum-sensing (QS) system, encoded on the virulence accessory gene regulator (ag...

Neonatal skin dysbiosis to infantile atopic dermatitis: Mitigating effects of skin care.

Reika Aoyama Seitaro Nakagawa Yoko Ichikawa Naohiro Inohara Yuriko Yamazaki Tomoka Ito Takashi Sugihira Michihiro Kono Masashi Akiyama Hiroki Takahashi Akiko Takaya Fumitaka Ichikawa Taiji Nakano Seiko Tanaka Yutaka Koyano Manabu Fujimoto Gabriel Núñez Naoki Shimojo Yuumi Nakamura

Allergy 2024年3月 [査読有り]

Total Synthesis of Dragmacidins G and H.

Keita Yamazaki Yuma Okuda Akiko Takaya Tetsuhiro Nemoto

Organic letters 26(3) 670-675 2024年1月 [査読有り]

The total synthesis of dragmacidins G and H was achieved for the first time by employing nucleophilic aromatic substitution and site-selective cross-coupling reactions using appropriately functionalized pyrazines as substrates. The evaluation of a...

High-Efficiency Single-Cell Containment Microdevices Based on Fluid Control

Daiki Tanaka Junichi Ishihara Hiroki Takahashi Masashi Kobayashi Aya Miyazaki Satsuki Kajiya Risa Fujita Naoki Maekawa Yuriko Yamazaki Akiko Takaya Yuumi Nakamura Masahiro Furuya Tetsushi Sekiguchi Shuichi Shoji

Micromachines 14(5) 1027-1027 2023年5月 [査読有り]

In this study, we developed a comb-shaped microfluidic device that can efficiently trap and culture a single cell (bacterium). Conventional culture devices have difficulty in trapping a single bacterium and often use a centrifuge to push the bacte...

Isolation of two new trichorzin PA derivatives, trichorzin PA X and XI, from the terrestrial fungus Trichoderma harzianum IFM 66736

Yasumasa Hara Teruhisa Manome Wataru Suehiro Shinji Harada Yoshikazu Yamagishi Akiko Takaya Yasumitsu Ogra Masami Ishibashi

Tetrahedron Letters 121 154488-154488 2023年4月 [査読有り]