大学院医学研究院

研究キーワード

社会認知機能 ,オキシトシン／バソプレシン ,神経認知機能 ,治療抵抗性統合失調症 ,統合失調症

研究分野

ライフサイエンス / 精神神経科学 /

受賞

2022年11月

日本臨床精神神経薬理学会, 学会奨励賞
築地茉莉子ら(共著)

2021年10月

日本臨床精神神経薬理学会, 学会奨励賞
仲田祐介

2019年10月

日本神経精神薬理学会, 学会奨励賞
仲田祐介

2018年10月

日本脳科学会, 学会奨励賞
仲田祐介

論文

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ドパミン過感受性精神病(DSP)を含む治療抵抗性統合失調症(TRS)患者を対象とする長半減期型非定型抗精神病薬(LAA)とクロザピン(CLZ)の有効性の検証

金原信久仲田祐介伊豫雅臣大迫鑑顕鈴木均木村大渡部芳徳比留間真由美井手本啓太田村真樹太田貴代光吉田泰介山中浩嗣青木勉斎賀孝久野々村司横山大輔

千葉医学雑誌 99(4) 113-113 2023年8月

Can brexpiprazole be switched safely in patients with schizophrenia and dopamine supersensitivity psychosis? A retrospective analysis in a real-world clinical practice

Fumiaki Yamasaki Nobuhisa Kanahara Yusuke Nakata Shinji Koyoshi Yuta Yanagisawa Takeru Saito Takahiro Oiwa Masanobu Kogure Tsuyoshi Sasaki Taisuke Yoshida Hiroshi Kimura Masaomi Iyo

Journal of Psychopharmacology 2023年7月

Background:

Several studies have reported that a switch to the dopamine partial agonist (DPA) aripiprazole (ARP), especially when the switch is abrupt, is likely to fail and sometimes worsen psychosis in schizophrenia patients already under high...

Taq1A polymorphism in patients with bipolar disorder: A candidate gene study based on the dopamine hypothesis

Kiyomitsu Ota Tomihisa Niitsu Kengo Oishi Keita Idemoto Maria Kato Jing Liu Masumi Tachibana Yusuke Nakata Masayuki Takase Yasunori Oda Masatomo Ishikawa Tasuku Hashimoto Nobuhisa Kanahara Yoshimi Iwayama Tomoko Toyota Takeo Yoshikawa Masaomi Iyo

Psychiatry Research Communications 3(2) 100124-100124 2023年6月

Dopamine supersensitivity psychosis and delay of clozapine treatment in patients with treatment-resistant schizophrenia.

Yuto Masumo Nobuhisa Kanahara Masanobu Kogure Fumiaki Yamasaki Yusuke Nakata Masaomi Iyo

International clinical psychopharmacology 38(2) 102-109 2023年3月

Both the underutilization of clozapine and treatment resistance of patients to clozapine are serious problems worldwide. Identifying clinical markers predicting response to clozapine would help clinicians more effectively utilize clozapine treatme...

Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia.

Masanobu Kogure Nobuhisa Kanahara Atsuhiro Miyazawa Yuki Shiko Ikuo Otsuka Koichi Matsuyama Masayuki Takase Makoto Kimura Hiroshi Kimura Kiyomitsu Ota Keita Idemoto Masaki Tamura Yasunori Oda Taisuke Yoshida Satoshi Okazaki Fumiaki Yamasaki Yusuke Nakata Yoshinori Watanabe Tomihisa Niitsu Akitoyo Hishimoto Masaomi Iyo

Frontiers in psychiatry 14 1334335-1334335 2023年

BACKGROUND: Most genetic analyses that have attempted to identify a locus or loci that can distinguish patients with treatment-resistant schizophrenia (TRS) from those who respond to treatment (non-TRS) have failed. However, evidence from multiple...