The liver stores glycogen and releases glucose into the blood upon increased energy demand. Group 2 innate lymphoid cells (ILC2) in adipose and pancreatic tissues are known for their involvement in glucose homeostasis, but the metabolic contributi...
Jesus M Gomez-Salinero Tomer Itkin Chaitanya Badwe Yang Lin Sean Houghton Balvir Kunar Graeme M Birdsey Victoria Kalna Neil Dufton Claire R Peghairx Masataka Yokoyama Matthew Wingo Ge Li Jenny Zhaoying Xiang Yen-Michael Sheng Hsu David Redmond Ryan Schreiner Anna M Randi Shahin Rafii
TAS4464, a potent, selective small molecule NEDD8-activating enzyme (NAE) inhibitor, leads to inactivation of cullin-RING E3 ubiquitin ligases (CRLs) and consequent accumulations of its substrate proteins. Here, we investigated the antitumor prope...
Brisa Palikuqi Duc-Huy T. Nguyen Ge Li Ryan Schreiner Alessandro F. Pellegata Ying Liu David Redmond Fuqiang Geng Yang Lin Jesus M. Gómez-Salinero Masataka Yokoyama Paul Zumbo Tuo Zhang Balvir Kunar Mavee Witherspoon Teng Han Alfonso M. Tedeschi Federico Scottoni Steven M. Lipkin Lukas Dow Olivier Elemento Jenny Z. Xiang Koji Shido Jason R. Spence Qiao J. Zhou Robert E. Schwartz Paolo De Coppi Sina Y. Rabbany Shahin Rafii
David M. Barry Elizabeth A. McMillan Balvir Kunar Raphael Lis Tuo Zhang Tyler Lu Edward Daniel Masataka Yokoyama Jesus M. Gomez-Salinero Angara Sureshbabu Ondine Cleaver Annarita Di Lorenzo Mary E. Choi Jenny Xiang David Redmond Sina Y. Rabbany Thangamani Muthukumar Shahin Rafii
Nature Communications 10(1) 2019年12月
Abstract
Although kidney parenchymal tissue can be generated in vitro, reconstructing the complex vasculature of the kidney remains a daunting task. The molecular pathways that specify and sustain functional, phenotypic and structural heterogenei...
大学院国際学術研究院