Journal of infection and chemotherapy 25(2) 124-128 2019年2月 [査読有り]
Bacterial meningitis is a life-threatening condition. Vancomycin (VCM) is one of the antibiotics used as empirical therapy for bacterial meningitis. It is essential to maintain an adequate concentration of VCM in cerebrospinal fluid (CSF) to treat...
JOURNAL OF INFECTION AND CHEMOTHERAPY 23(12) 848-851 2017年12月 [査読有り]
Because there is little absorption of orally administered vancomycin hydrochloride (VCM) through the normal intestinal microvillus membrane, the pharmacokinetics of VCM absorbed from the digestive tract are mostly unknown. Here we report a case of...
Drug Metabolism and Pharmacokinetics 28(3) 265-268 2013年12月 [査読有り]
Treatment with benzbromarone (BBR), a potent uricosuric drug, can be associated with liver injury. Recently, we reported that culture of human hepatocellular carcinoma FLC-4 cells on micro-space cell culture plates could increase the functional ex...