OBJECTIVES: IgG4-related disease (IgG4-RD) is a systemic autoimmune disease with an unknown etiology, affecting single/multiple organ(s). Pathological findings include the infiltration of IgG4-producing plasma cells, obliterative phlebitis, and st...
Allergology international : official journal of the Japanese Society of Allergology 2024年2月
BACKGROUND: This study aimed to clarify the diagnostic and predictive factors for perennial allergic rhinitis (PAR) onset in children by analyzing the results of the Chiba High-risk Birth Cohort for Allergy study, which examined newborns with a fa...
Jin Kumagai Masahiro Kiuchi Kota Kokubo Hiroyuki Yagyu Masahiro Nemoto Kaori Tsuji Ken Nagahata Atsushi Sasaki Takahisa Hishiya Miki Onoue Rie Shinmi Yuri Sonobe Tomohisa Iinuma Syuji Yonekura Jun Shinga Toyoyuki Hanazawa Haruhiko Koseki Toshinori Nakayama Koutaro Yokote Kiyoshi Hirahara
Proceedings of the National Academy of Sciences of the United States of America 120(49) e2302903120 2023年12月 [査読有り]
Uncontrolled type 2 immunity by type 2 helper T (Th2) cells causes intractable allergic diseases; however, whether the interaction of CD4+ T cells shapes the pathophysiology of allergic diseases remains unclear. We identified a subset of Th2 cells...
大学院国際学術研究院