The prognostic value of mixed venous oxygen tension (PvO2) at pulmonary hypertension diagnosis treated with selective pulmonary vasodilators remains unclear. This study sought to investigate the association of Pv...
Yumiko Ikubo Takayuki Jujo Sanada Koji Hosomi Jonguk Park Akira Naito Hiroki Shoji Tomoko Misawa Rika Suda Ayumi Sekine Toshihiko Sugiura Ayako Shigeta Hinako Nanri Seiichiro Sakao Nobuhiro Tanabe Kenji Mizuguchi Jun Kunisawa Takuji Suzuki Koichiro Tatsumi
BMC pulmonary medicine 22(1) 138-138 Apr 2022 [Refereed]
Abstract
Background
The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is considered to be associated with chronic inflammation; however, the underlying mechanism remains unclear. Recently, altered gut microbiota were fo...
Tu L Desroches-Castan A Mallet C Guyon L Cumont A Phan C Robert F Thuillet R Bordenave J Sekine A Huertas A Ritvos O Savale L Feige JJ Humbert M Bailly S Guignabert C
Circulation research 124(6) 846-855 Mar 2019 [Refereed]
Toshio Suzuki Yuji Tada Rintaro Nishimura Takeshi Kawasaki Ayumi Sekine Takashi Urushibara Fumiaki Kato Taku Kinoshita Jun Ikari James West Koichiro Tatsumi
American Journal of Physiology - Lung Cellular and Molecular Physiology 310(11) L1185-L1198 Jun 2016
Pulmonary vascular endothelial function may be impaired by oxidative stress in endotoxemia-derived acute lung injury. Growing evidence suggests that endothelial-to-mesenchymal transition (EndMT) could play a pivotal role in various respiratory dis...
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