Kiyoshi Hirahara Kota Kokubo Ami Aoki Masahiro Kiuchi Toshinori Nakayama
Frontiers in Immunology 12 Apr 2021 [Refereed]
Memory T cells are crucial for both local and systemic protection against pathogens over a long period of time. Three major subsets of memory T cells; effector memory T (TEM) cells, central memory T (TCM) cells, and tissue-re...
Masahiro Kiuchi Atsushi Onodera Kota Kokubo Tomomi Ichikawa Yuki Morimoto Eiryo Kawakami Naoya Takayama Koji Eto Haruhiko Koseki Kiyoshi Hirahara Toshinori Nakayama
Journal of Experimental Medicine 218(4) Apr 2021 [Refereed]
Different dynamics of gene expression are observed during cell differentiation. In T cells, genes that are turned on early or turned off and stay off have been thoroughly studied. However, genes that are initially turned off but then turned on aga...
Ami Aoki Kiyoshi Hirahara Masahiro Kiuchi Toshinori Nakayama
Allergology International 70(1) 3-8 Jan 2021 [Refereed]
Eosinophils are multifunctional leukocytes, being involved in the host defense against helminth infection, tissue homeostasis and repair of injured tissue. However, eosinophils also play critical roles in shaping the pathogenesis of allergic disea...
Mucosal Immunology 14(3) 640-651 Dec 2020 [Refereed]
<title>Abstract</title>Oral immunotherapy (OIT) is an effective approach to controlling food allergy. Although the detailed molecular and cellular mechanisms of OIT are unknown currently, they must be understood to advance the treatment of allergi...
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