S. Joo   Y. Fukuyama   E. J. Park   Y. Yuki   Y. Kurashima   R. Ouchida   S. F. Ziegler   H. Kiyono   
MUCOSAL IMMUNOLOGY 10(4) 901-911 2017年7月 [査読有り]
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7)-like cytokine involved in T helper 2 type immune responses. The primary target of TSLP is myeloid dendritic cells (DCs), however, little is known about the mechanism by which TSLP elic...
EXPERT REVIEW OF VACCINES 16(12) 1231-1240 2017年 [査読有り]
Introduction: Nasal vaccination is one of the most effective immunization methods because it can induce effective antigen-specific immune responses not only at the mucosal site of administration but also at distant mucosal surfaces, as well as in ...
Rika Ouchida   Qing Lu   Jun Liu   Yingqian Li   Yiwei Chu   Takeshi Tsubata   Ji-Yang Wang   
JOURNAL OF IMMUNOLOGY 194(7) 3096-3101 2015年4月 [査読有り]
The IgM FcR (Fc mu R) promotes B cell survival, but the molecular mechanism remains largely unknown. We show using Fc mu R-/- and wild-type mice that Fc mu R specifically enhanced B cell survival induced by BCR cross-linking with F(ab ')(2)-anti-I...
IMMUNOLOGY AND CELL BIOLOGY 92(6) 527-534 2014年7月 [査読有り]
The lysosomal protein LAPTM5 has been shown to negatively regulate cell surface T cell receptor (TCR) expression and T-cell activation by promoting CD3 zeta degradation in lysosomes, but the mechanism remains largely unknown. Here we show that LAP...