○○学科

研究キーワード

男性不妊症 ,遺伝学 ,前立腺癌

研究分野

ライフサイエンス / 泌尿器科学 /

経歴

2022年4月

-

現在

千葉大学医学部附属病院千葉県がん・生殖医療相談支援センターセンター長

2017年4月

-

現在

千葉大学医学部附属病院遺伝子診療部部長

2004年4月

-

現在

千葉大学大学院医学研究院泌尿器科学教授

学歴

1985年4月

-

1989年3月

千葉大学医学研究科外科系泌尿器科学

1978年4月

-

1984年3月

千葉大学医学部

受賞

1999年

日本医師会医師研究助成費

1997年

第2回ゐのはな同窓会賞学術賞

1997年

第6回社団法人日本泌尿器科学会研究助成金

1992年

第1回社団法人日本泌尿器科学会研究助成金

1955年

佐川がん研究助成金

論文

12 3 4 5 >

Chromatin activation with H3K36me2 and compartment shift in metastatic castration-resistant prostate cancer

Sanji Kanaoka Atsushi Okabe Manato Kanesaka Bahityar Rahmutulla Masaki Fukuyo Motoaki Seki Takayuki Hoshii Hiroaki Sato Yusuke Imamura Shinichi Sakamoto Tomohiko Ichikawa Atsushi Kaneda

Cancer Letters 588 216815-216815 2024年4月

Testosterone bounce predicts favorable prognoses for prostate cancer patients treated with degarelix.

Shuhei Kamada Shinichi Sakamoto Ryo Kinoshita Xue Zhao Tomohiko Kamasako Ryosuke Yamase Rii Junryo Shinpei Saito Pae Sangjon Akinori Takei Yasutaka Yamada Yusuke Goto Yusuke Imamura Taro Iguchi Atsushi Mizokami Hiroyoshi Suzuki Koichiro Akakura Tomohiko Ichikawa

The Prostate 2024年2月

BACKGROUND: To clarify the clinical roles of changes in testosterone (T) levels with a cut-off level of 20 ng/dL as predictive factors for prostate cancer patients treated with degarelix acetate. METHODS: A total of 120 prostate cancer patients wh...

Copy Number Gain in Androgen Receptors Predicts the Poor Prognosis in Japanese Castration-resistant Prostate Cancer.

Shinichi Sakamoto Keisuke Ando Sangjon Pae Xue Zhao Kazuko Sakai Kodai Sato Shinpei Saito Yasutaka Yamada Junryo Rii Yusuke Goto Tomokazu Sazuka Yusuke Imamura Naohiko Anzai Koichiro Akakura Kazuto Nishio Tomohiko Ichikawa

Anticancer research 44(2) 639-647 2024年2月

BACKGROUND/AIM: The prognostic significance of androgen receptor amplification (AR amp) in cell-free DNA (cfDNA) was studied in Japanese patients with castration-resistant prostate cancer (CRPC). PATIENTS AND METHODS: A total of 120 serum samples ...

Novel nerve-sparing robot-assisted radical prostatectomy with endopelvic fascia preservation and long-term outcomes for a single surgeon.

Masafumi Maruo Yusuke Goto Kanetaka Miyazaki Atsushi Inoue Koichiro Kurokawa Akiko Enomoto Satoki Tanaka Sota Katsura Sho Sugawara Miki Fuse Kazuto Chiba Yusuke Imamura Shinichi Sakamoto Maki Nagata Tomohiko Ichikawa

Scientific reports 14(1) 926-926 2024年1月

Although novel techniques for avoiding incontinence during robot-assisted radical prostatectomy have been developed, long-term oncological outcomes are unknown. The objective of this study was to determine the long-term oncological outcomes and fu...

L-type amino acid transporter 1 inhibitor JPH203 prevents the growth of cabazitaxel-resistant prostate cancer by inhibiting cyclin-dependent kinase activity.

Junryo Rii Shinichi Sakamoto Atsushi Mizokami Minhui Xu Ayumi Fujimoto Shinpei Saito Hidekazu Koike Takaaki Tamura Takayuki Arai Yasutaka Yamada Yusuke Goto Tomokazu Sazuka Yusuke Imamura Kazuhiro Suzuki Yoshikatsu Kanai Naohiko Anzai Tomohiko Ichikawa

Cancer science 2024年1月

L-type amino acid transporter 1 (LAT1, SLC7A5) is an amino acid transporter expressed in various carcinomas, and it is postulated to play an important role in the proliferation of cancer cells through the uptake of essential amino acids. Cabazitax...