Yasunori Fukumoto   Masayoshi Ikeuchi   Liang Qu   Tyuji Hoshino   Naoto Yamaguchi   Yuji Nakayama   Yasumitsu Ogra   
The Journal of biological chemistry 297(2) 100831-100831 2021年8月
The ATR pathway is one of the major DNA damage checkpoints, and Rad17 is a DNA-binding protein that is phosphorylated upon DNA damage by ATR kinase. Rad17 recruits the 9-1-1 complex that mediates the checkpoint activation, and proteasomal degradat...