Journal of immunology (Baltimore, Md. : 1950) 2024年4月
Attempts have been made to elucidate the functional markers of regulatory T cells (Tregs), CD4+Foxp3+ T cells with an immunosuppressive function. Sialyl Lewis X (sLex), a tetrasaccharide Ag, is involved in leukocyte trafficking as selectin ligands...
Lymphocyte homing to peripheral lymph nodes (PLN) is critical for immune surveillance. However, autoimmune diseases such as multiple sclerosis (MS) can occur due to excessive immune responses in the PLN. Here we show that 6-sulfo sialyl...
Frontiers in Cell and Developmental Biology 11 2023年11月
The intestinal epithelium is the first line of host defense, and its homeostasis is dependent on soluble factors that comprise the crypt niche. Antimicrobial proteins are one of the mediators to maintain gut homeostasis. Angiogenin-4 (Ang4) is a m...
Fukuda M(担当:分担執筆, 範囲:Determination of chemokine-glycosaminoglycan interaction specificity 416:254-263,Functions of glycans revealed by gene inactivation of L-selectin ligand sulfotransferases in mice 416:279-290)