International journal of molecular sciences 22(16) 2021年8月 [査読有り]
The second messenger 2'3'-cyclic-GMP-AMP (cGAMP) is thought to be transmitted from brain carcinomas to astrocytes via gap junctions, which functions to promote metastasis in the brain parenchyma. In the current study, we established a method to in...
Despite progress in the use of hyperthermia in clinical practice, the thermosensitivity of cancer cells is poorly understood. In a previous study, we found that sensitivity to hyperthermia varied between ovarian and uterine cancer cell lines. Upon...
Riki Cho Yu Sakurai Haleigh Sakura Jones Hidetaka Akita Akihiro Hisaka Hiroto Hatakeyama
Cancers 12(12) 2020年12月 [査読有り]
Despite the promising anticancer effects of immune checkpoint inhibitors, their low objective response rate remains to be resolved; thus, combination therapies have been investigated. We investigated the combination of an anti-programmed cell deat...
Global differences in changes in the numbers of population-adjusted daily test-positive cases (NPDP) and deaths (NPDD) by COVID-19 were analyzed for 49 countries, including developed and developing countries. The changes as a proportion of nationa...
Khalil IA, Hatakeyama H, Nakamura T, Harashima H(担当:分担執筆, 範囲:A Multifunctional Envelope-type Nano Device for Cancer Therapy)
Springer 2019年 （ISBN:9784431568803） [査読有り]
This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology. The current studies based on molecular and cellular biology while ignoring pathophys...
大学院国際学術研究院