Biochimica et biophysica acta. Molecular and cell biology of lipids 1865(6) 158675-158675 2020年6月 [査読有り]
Ceramide kinase (CerK) phosphorylates ceramide to ceramide-1-phosphate (C1P), a bioactive sphingolipid. Since the mechanisms responsible for regulating the proliferation and migration/metastasis of cancer cells by the CerK/C1P pathway remain uncle...
Qizhen Cao   Wanqin Wang   Min Zhou   Qian Huang   Xiaoxia Wen   Jun Zhao   Sixiang Shi   Ku Geng   Fenge Li   Hiroto Hatakeyama   Chunyu Xu   David Piwnica-Worms   Weiyi Peng   Dapeng Zhou   Anil K Sood   Chun Li   
Nanomedicine : nanotechnology, biology, and medicine 25 102169-102169 2020年4月 [査読有り]
Generation of durable tumor-specific immune response without isolation and expansion of dendritic cells or T cells ex vivo remains a challenge. In this study, we investigated the impact of nanoparticle-mediated photothermolysis in combination with...
Journal for immunotherapy of cancer 8(1) 2020年2月 [査読有り]
BACKGROUND: Recently, antiprogrammed cell death protein 1 (aPD-1) and antiprogrammed death-ligand 1 (aPD-L1) monoclonal antibodies (mAbs) have been approved. Even though aPD-1 and aPD-L1 mAbs target the same PD-1/PD-L1 axis, it is still unclear wh...
Khalil IA, Hatakeyama H, Nakamura T, Harashima H(担当:分担執筆, 範囲:A Multifunctional Envelope-type Nano Device for Cancer Therapy)
Springer 2019年 (ISBN:9784431568803) [査読有り]
This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology. The current studies based on molecular and cellular biology while ignoring pathophys...