日本薬物動態学会, DMPK論文賞1st place,Plausible drug interaction between cyclophosphamide and voriconazole via inhibition of CYP2B6柴田侑裕 爲本雄太 Sheelendra Pratap Singh 吉友葵 保月静香 佐藤洋美 樋坂章博
Miaki Uzu   Wun Chey Sin   Ayaka Shimizu   Hiromi Sato   
International Journal of Molecular Sciences 19(4) 2018年4月 [査読有り]
The tumor microenvironment is known to have increased levels of cytokines and metabolites, such as glutamate, due to their release from the surrounding cells. A normal cell around the tumor that responds to the inflammatory environment is likely t...
Saki Kaneko   Chiaki Sato   Nobuya Shiozawa   Ayami Sato   Hiromi Sato   Nantiga Virgona   Tomohiro Yano   
Anticancer Research 38(3) 1391-1399 2018年3月 [査読有り]
Background/Aim: A hallmark of the progression of prostate cancer to advanced disease is the acquisition of androgen-independent growth. This malignant phenotype is characterized by resistance to conventional treatments and predisposes to formation...
Biological and Pharmaceutical Bulletin 41(4) 619-627 2018年 [査読有り]
Acquired resistance to sunitinib is a challenge in the treatment of renal cell carcinoma (RCC). The dys-regulation of cellular metabolism is prevalent during resistance acquisition. It is known that in sunitinib-resistant RCC 786-O (786-O Res) cel...
Till Ploenes   Mitja Fischer   Kerstin Hoehne   Hiromi Sato   Joachim Mueller-Quernheim   Gernot Zissel   
PATHOLOGY & ONCOLOGY RESEARCH 23(4) 723-730 2017年10月 [査読有り]
Malignant pleural mesothelioma (MPM) is a highly aggressive tumor that arises from the surface of the pleura and is associated with a history of asbestos exposure. The tumor is characterized by a strong local invasiveness and a poor response to an...