Hiromi Sato

Name	Hiromi Sato
URL
Affiliation	Chiba University
Section	Lab of Clinical Pharmacology & Pharmacometrics, Graduate School of Pharmaceutical Sciences
Job title	Associate professor
Degree	博士（薬学）(千葉大学)
J-Global ID	201901006027076622

Research Interests

cancer drug resistance ,brain cancer ,tumor microenvironment ,astrocyte ,metabolic flux analysis ,connexin ,gap junction ,metabolome ,sex differences ,aging ,drug-drug interaction ,modeling and simulation ,MBMA ,diabetes mellitus ,CVR ,adipose inflammation ,drug absorption

Research Areas

Life sciences / Pharmacology / applied phharmacology, quantitative systems pharmacology
Life sciences / Clinical pharmacy / 薬物治療

Research History

Oct 2023

Today

Chiba University Graduate School of Pharmaceutical Sciences Associate professor

Mar 2018

Sep 2023

Chiba University Graduate School of Pharmaceutical Sciences Lecturer

Apr 2008

Feb 2018

Chiba University Graduate School of Pharmaceutical Sciences Assistant professor

Apr 2011

Jun 2011

The University of British Columbia The Life Sciences Institute(Acceptance: Prof. Christian C. Naus) Visiting scientist

Education

Apr 2006

Mar 2008

Chiba University Graduate School of Pharmaceutical Sciences Ph.D. (Pharmaceutical Sciences)

Apr 2004

Mar 2006

Chiba University Graduate School of Pharmaceutical Sciences Master of Sciences (Medical Pharmacy)

Apr 2000

Mar 2004

Chiba University Faculty of Pharmaceutical Sciences

Committee Memberships

12 >

Dec 2022

Today

日本臨床薬理学会評議員

Jul 2022

Today

日本毒性学会評議員

Mar 2022

Today

日本性差医学・医療学会評議員

2013

Today

日本薬学会薬理系薬学部会若手世話人

2012

Today

日本薬理学会学術評議員

Awards

12 >

Oct 2022

DMPK award 1st place
Yukihiro Shibata Yuta Tamemoto Sheelendra Pratap Singh Aoi Yoshitomo Shizuka Hozuki Hiromi Sato Akihiro Hisaka

Mar 2022

日本薬学会, 令和3年度日本薬学会薬理系薬学部会奨励賞,がん治療抵抗性におけるgap junctionの関与
佐藤洋美

Jun 2019

12th Research Award of Japan Reserch Foundation Clinical Pharmacology
Hiromi Sato Shizuka Hozuki Yukihiro Shibata Akihiro Hisaka

Jan 2017

日本性差医学・医療学会, 第10回日本性差医学・医療学会優秀ポスター賞,NBDレセプト情報オープンデータにみる薬剤提供実態の男女差
上野光一佐藤洋美

Mar 2015

千葉東洋医学シンポジウム, 第40回千葉東洋医学シンポジウム優秀発表賞,更年期障害患者における桂枝茯苓丸治療効果に関するエストロゲン受容体遺伝子多型の関与
佐藤洋美

Papers

12 3 4 5 >

Model-based meta-analysis of ethnic differences and their variabilities in clearance of oral drugs classified by clearance mechanism

Sato H Marutani R Takaoka R Mori-Fegan D Wang X Maeda K Kusuhara H Suzuki H Yoshioka H Hisaka A

CPT: Pharmacometrics & Systems Pharmacology 12(8) 1132-1142 2023

In this study, the ethnic ratios (ERs) of oral clearance between Japanese and Western populations were subjected to model-based meta-analysis (MBMA) for 81 drugs evaluated in 673 clinical studies. The drugs were classified into eight groups accord...

Integrated use of in vitro and in vivo information for comprehensive prediction of drug interactions due to inhibition of multiple CYP isoenzymes

Hozuki S Yoshioka H Asano S Nakamura M Koh S Shibata Y Tamemoto Y Sato H Hisaka A

Clinical Pharmacokinetics 2023 [Refereed]

Involvement of multiple cytochrome P450 isoenzymes in drug interactions between ritonavir and direct oral anticoagulants.

Tamemoto Y Shibata Y Hashimoto N Sato H Hisaka A

Drug Metabolism and Pharmacokinetics 53 100498-100498 2023 [Refereed]

Significance of basal membrane permeability of epithelial cells in predicting intestinal drug absorption.

Yoshitomo A Asano S Hozuki S Tamemoto Y Shibata Y Hashimoto N Takahashi K Sasaki Y Ozawa N Kageyama M Iijima T Kazuki Y Sato H Hisaka A

Drug Metabolism and Disposition 51(3) 318-328 2023 [Refereed]

Kuretake Soejima Hiromi Sato Akihiro Hisaka

Clinical pharmacokinetics 61(2) 295-305 Feb 2022 [Refereed]

OBJECTIVE: This study aimed to examine the magnitude of age-related change in hepatic clearance by integrating the data of multiple drugs and to compare this with renal clearance, considering associations with age-related changes in organ weight a...