Dr. Kiyono obtained his dental degree (D.D.S.) from Nihon University, and Ph. D. from the University of Alabama at Birmingham (UAB). His background as a dentist combined with extensive research experience in the field of Mucosal Immunology at UAB, Max-Planck Institute, Osaka University and now, the University of Tokyo make him exceptionally well qualified to lead the current and future directions of mucosal immunology and mucosal vaccine. To reflect his scientific contribution, he has been listed in ISI Highly Cited Researchers’ List since 2005. He is the past President of Society for Mucosal Immunology. He received of several prestigious awards including NIH New Investigator Research Award, NIH Research Career Development Award, The Japanese Society for Vaccinology Takahashi Award, and Hideyo Noguchi Memorial Medical Science Award. He has a total of 422 publications in peer review journals and edited a total of 20 books. He is currently Dean, the Institute of Medical Science, the University of Tokyo.
NIH New Investigator Research Award (1984-1987) NIH Rerearch Career Development Award (1988-1993) ISI Highly Cited Resercher’s List (2005-Present) The 51st Dr. Hideyo Noguchi Memorial Medical Science Awad (2007) The 2nd Japanese Society for Vaccinolog・・・
Mariko Kamioka Yoshiyuki Goto Kiminori Nakamura Yuki Yokoi Rina Sugimoto Shuya Ohira Yosuke Kurashima Shingo Umemoto Shintaro Sato Jun Kunisawa Yu Takahashi Steven E. Domino Jean-Christophe Renauld Susumu Nakae Yoichiro Iwakura Peter B. Ernst Tokiyoshi Ayabe Hiroshi Kiyono
Proceedings of the National Academy of Sciences 119(3) 2022年1月
Significance
Paneth cells produce granules containing antimicrobial peptides, such as α-defensin for host defense. Examination of the production and utilization of fucosyltransferase 2 (Fut2) by Paneth cells revealed two distinct subsets: Fut2 <...
Nontypeable Haemophilus influenzae (NTHi) strains form a major group of pathogenic bacteria that colonizes the nasopharynx and causes otitis media in young children. At present, there is no licensed vaccine for NTHi. Because NTHi colonizes the upp...
<title>Abstract</title>Increases in adhesive and invasive commensal bacteria, such as <italic>Escherichia coli</italic>, and subsequent disruption of the epithelial barrier is implicated in the pathogenesis of inflammatory bowel disease (IBD). How...
The oral and nasal cavities are covered by the mucosal epithelium that starts at the beginning of the aero-digestive tract. These mucosal surfaces are continuously exposed to environmental antigens including pathogens and allergens and ...
Intestinal inflammation can be accompanied by osteoporosis, but their relationship, mediated by immune responses, remains unclear. Here, we investigated a non-IgE-mediated food-allergic enteropathy model of ovalbumin (OVA) 23-3 mice expressing OVA...
So-Ichiro Hirata Takahiro Nagatake Kento Sawane Koji Hosomi Tetsuya Honda Sachiko Ono Noriko Shibuya Emiko Saito Jun Adachi Yuichi Abe Junko Isoyama Hidehiko Suzuki Ayu Matsunaga Takeshi Tomonaga Hiroshi Kiyono Kenji Kabashima Makoto Arita Jun Kunisawa
Allergy 2020年2月
BACKGROUND: Maternal dietary exposures are considered to influence the development of infant allergies through changes in the composition of breast milk. Cohort studies have shown that ω3 PUFA in breast milk may have a beneficial effect on the pre...
Secretory immunoglobulin A, the most abundant antibody isotype in the body, maintains a mutual relationship with commensal bacteria and acts as a primary barrier at the mucosal surface. Colonization by commensal bacteria induces an IgA response, a...
大学院国際学術研究院