Dr. Kiyono obtained his dental degree (D.D.S.) from Nihon University, and Ph. D. from the University of Alabama at Birmingham (UAB). His background as a dentist combined with extensive research experience in the field of Mucosal Immunology at UAB, Max-Planck Institute, Osaka University and now, the University of Tokyo make him exceptionally well qualified to lead the current and future directions of mucosal immunology and mucosal vaccine. To reflect his scientific contribution, he has been listed in ISI Highly Cited Researchers’ List since 2005. He is the past President of Society for Mucosal Immunology. He received of several prestigious awards including NIH New Investigator Research Award, NIH Research Career Development Award, The Japanese Society for Vaccinology Takahashi Award, and Hideyo Noguchi Memorial Medical Science Award. He has a total of 422 publications in peer review journals and edited a total of 20 books. He is currently Dean, the Institute of Medical Science, the University of Tokyo.
NIH New Investigator Research Award (1984-1987) NIH Rerearch Career Development Award (1988-1993) ISI Highly Cited Resercher’s List (2005-Present) The 51st Dr. Hideyo Noguchi Memorial Medical Science Awad (2007) The 2nd Japanese Society for Vaccinolog・・・
Rui Tada Miki Ogasawara Daisuke Yamanaka Yasuhiro Sakurai Yoichi Negishi Hiroshi Kiyono Naohito Ohno Jun Kunisawa Yukihiko Aramaki
PloS one 16(2) e0246422 2021年 [査読有り]
Despite significant modern medicine progress, having an infectious disease is a major risk factor for humans. Mucosal vaccination is now widely considered as the most promising strategy to defeat infectious diseases; however, only live-attenuated ...
Zilai Liu Koji Hosomi Atsushi Shimoyama Ken Yoshii Xiao Sun Huangwenxian Lan Yunru Wang Haruki Yamaura Davie Kenneth Azusa Saika Takahiro Nagatake Hiroshi Kiyono Koichi Fukase Jun Kunisawa
Frontiers in pharmacology 12 763657-763657 2021年 [査読有り]
We previously identified Alcaligenes spp. as a commensal bacterium that resides in lymphoid tissues, including Peyer's patches. We found that Alcaligenes-derived lipopolysaccharide acted as a weak agonist of Toll-like receptor four due to the uniq...
Yunru Wang Koji Hosomi Atsushi Shimoyama Ken Yoshii Takahiro Nagatake Yukari Fujimoto Hiroshi Kiyono Koichi Fukase Jun Kunisawa
Frontiers in immunology 12 699349-699349 2021年 [査読有り]
Alcaligenes spp., including A. faecalis, is a gram-negative facultative bacterium uniquely residing inside the Peyer's patches. We previously showed that A. faecalis-derived lipopolysaccharides (Alcaligenes LPS) acts as a weak agonist of toll-like...
BackgroundWe have previously developed a rice-based oral vaccine against cholera diarrhea, MucoRice-CTB. Using Agrobacterium-mediated co-transformation, we produced the selection marker-free MucoRice-CTB line 51A, which has three copies of the cho...
So-Ichiro Hirata Takahiro Nagatake Kento Sawane Koji Hosomi Tetsuya Honda Sachiko Ono Noriko Shibuya Emiko Saito Jun Adachi Yuichi Abe Junko Isoyama Hidehiko Suzuki Ayu Matsunaga Takeshi Tomonaga Hiroshi Kiyono Kenji Kabashima Makoto Arita Jun Kunisawa
Allergy 2020年2月
BACKGROUND: Maternal dietary exposures are considered to influence the development of infant allergies through changes in the composition of breast milk. Cohort studies have shown that ω3 PUFA in breast milk may have a beneficial effect on the pre...
Secretory immunoglobulin A, the most abundant antibody isotype in the body, maintains a mutual relationship with commensal bacteria and acts as a primary barrier at the mucosal surface. Colonization by commensal bacteria induces an IgA response, a...
大学院国際学術研究院