Herein, we investigated the effect of the solubilizers, cetyltrimethylammonium bromide (CTAB) and amino methacrylate copolymer (Eudragit E PO, EUD-E), on the apparent amorphous solubility of ketoprofen (KTP) and free KTP concentrations in an aqueo...
Langmuir : the ACS journal of surfaces and colloids 38(34) 10454-10464 2022年8月
In this study, we prepared drug-loaded nanocarriers made of cholesteryl oleate (ChO) and γ-cyclodextrin (γ-CD). A nanosuspension (nanosuspension-I, NS-I) containing nanoparticles with a mean size of approximately 170 nm was obtained through the so...
Crystallization of organic molecules is important in a wide range of scientific disciplines. However, in contrast to maturely studied crystallization of inorganic materials, the crystallization mechanisms of organic molecules involving nucleation ...
Cas9 ribonucleoprotein (Cas9 RNP) is a promising genome editing tool, however its biological utility reuires the development of safe, efficient, and easy-to-use non-viral carriers. Cas9 RNP has a complicated conformation and charge distribution, r...