黒住顕

研究者氏名	黒住顕
	クロズミアキラ
URL
所属	千葉大学
部署	大学院医学研究院
職名	特任助教
科研費研究者番号	10710543
J-Global ID	202001002135003238

研究キーワード

ノンコーディングRNA ,マイクロRNA ,去勢抵抗性前立腺癌

研究分野

ライフサイエンス / 泌尿器科学 /

経歴

2020年9月

現在

千葉大学医学部附属病院泌尿器科特任助教

2017年12月

2020年9月

ジョンズホプキンズ大学泌尿器科リサーチフェロー

2017年4月

2017年11月

千葉大学医学部附属病院泌尿器科助教

学歴

2002年4月

2008年3月

千葉大学医学部医学科

論文

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Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma.

Takayuki Arai Atsushi Okato Satoko Kojima Tetsuya Idichi Keiichi Koshizuka Akira Kurozumi Mayuko Kato Kazuto Yamazaki Yasuo Ishida Yukio Naya Tomohiko Ichikawa Naohiko Seki

Cancer science 108(10) 2088-2101 2017年10月 [査読有り]

Analysis of our original microRNA (miRNA) expression signature of patients with advanced renal cell carcinoma (RCC) showed that microRNA-10a-5p (miR-10a-5p) was significantly downregulated in RCC specimens. The aims of the present study were to in...

Dual Strands of Pre-miR-149 Inhibit Cancer Cell Migration and Invasion through Targeting FOXM1 in Renal Cell Carcinoma.

Atsushi Okato Takayuki Arai Yasutaka Yamada Sho Sugawara Keiichi Koshizuka Lisa Fujimura Akira Kurozumi Mayuko Kato Satoko Kojima Yukio Naya Tomohiko Ichikawa Naohiko Seki

International journal of molecular sciences 18(9) 2017年9月 [査読有り]

Our recent studies revealed that dual strands of certain pre-microRNAs, e.g., pre-miR-144, pre-miR-145, and pre-miR-150, act as antitumor microRNAs (miRNAs) in several cancers. The involvement of passenger strands of miRNAs in cancer pathogenesis ...

Regulation of ITGA3 by the anti-tumor miR-199 family inhibits cancer cell migration and invasion in head and neck cancer.

Keiichi Koshizuka Toyoyuki Hanazawa Naoko Kikkawa Takayuki Arai Atsushi Okato Akira Kurozumi Mayuko Kato Koji Katada Yoshitaka Okamoto Naohiko Seki

Cancer science 108(8) 1681-1692 2017年8月 [査読有り]

For patients with head and neck squamous cell carcinoma (HNSCC), survival rates have not improved due to local recurrence and distant metastasis. Current targeted molecular therapies do not substantially benefit HNSCC patients. Therefore, it is ne...

Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer.

Yusuke Goto Akira Kurozumi Takayuki Arai Nijiro Nohata Satoko Kojima Atsushi Okato Mayuko Kato Kazuto Yamazaki Yasuo Ishida Yukio Naya Tomohiko Ichikawa Naohiko Seki

British journal of cancer 117(3) 409-420 2017年7月 [査読有り]

BACKGROUND: Despite recent advancements, metastatic castration-resistant prostate cancer (CRPC) is not considered curative. Novel approaches for identification of therapeutic targets of CRPC are needed. METHODS: Next-generation sequencing revealed...

Dual strands of pre-miR‑150 (miR‑150‑5p and miR‑150‑3p) act as antitumor miRNAs targeting SPOCK1 in naïve and castration-resistant prostate cancer.

Atsushi Okato Takayuki Arai Satoko Kojima Keiichi Koshizuka Yusaku Osako Tetsuya Idichi Akira Kurozumi Yusuke Goto Mayuko Kato Yukio Naya Tomohiko Ichikawa Naohiko Seki

International journal of oncology 51(1) 245-256 2017年7月 [査読有り]

Analysis of our microRNA (miRNA) expression signature in human cancers has shown that guide and passenger strands of pre-miR‑150, i.e., miR‑150‑5p and miR‑150‑3p, are significantly downregulated in cancer tissues. In miRNA biogenesis, the passenge...