大学院医学研究院

研究分野

ライフサイエンス / 膠原病、アレルギー内科学 /

経歴

2020年8月

-

現在

カリフォルニア大学サンディエゴ校

2009年10月

-

現在

千葉大学大学院医学研究院アレルギー・臨床免疫学教授

2018年

University of Southern California

2005年4月

千葉大学大学院医学研究院教授（遺伝子制御学）

1999年11月

-

2005年3月

千葉大学医学部助手（内科学第二）

論文

<2 345 6 >

Relationship of systemic type I interferon activity with clinical phenotypes, disease activity, and damage accrual in systemic lupus erythematosus in treatment-naive patients: a retrospective longitudinal analysis

Kazusa Miyachi Taro Iwamoto Shotaro Kojima Tomoaki Ida Junya Suzuki Takuya Yamamoto Norihiro Mimura Takahiro Sugiyama Shigeru Tanaka Shunsuke Furuta Kei Ikeda Kotaro Suzuki Timothy B. Niewold Hiroshi Nakajima

Arthritis Research & Therapy 25(1) 2023年2月

Abstract

Background

Systemic lupus erythematosus (SLE) is heterogeneous in organ involvement and disease severity, presenting a broad clinical phenotype. Systemic type I interferon (IFN) activity has been shown to be associated with lupus neph...

Prevalence and risk factors of osteonecrosis of the femoral head in patients with ANCA-associated vasculitis: a multicentre cohort study.

Norihiro Mimura Taro Iwamoto Shunsuke Furuta Kei Ikeda Yoshihisa Kobayashi Takayuki Nakamura Aiko Saku Shin-Ichiro Kagami Ayako Matsuki Kentaro Takahashi Takeshi Umibe Daiki Nakagomi Yoshie Sanayama Toyohiko Sugimoto Masashi Fukuta Masaki Hiraguri Hirotoshi Kawashima Koichi Hirose Hiroaki Takatori Kenichi Suehiro Shigekazu Takahashi Tomohiro Tamachi Manami Kato Fumiyoshi Takizawa Yuya Kawarai Shigeo Hagiwara Junichi Nakamura Seiji Ohtori Hiroshi Nakajima

RMD open 9(1) 2023年2月

OBJECTIVE: We aimed to determine the prevalence and risk factors for osteonecrosis of the femoral head (ONFH) in a multicentre cohort of patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). METHODS: One hundred and eighty...

Prognosis of spontaneous pneumomediastinum occurring in dermatomyositis or polymyositis patients with interstitial lung disease according to antimelanoma differentiation-associated gene 5 antibody status: a retrospective cohort study

Kazuya Abe Shunsuke Furuta Yoshihisa Kobayashi Takao Sugiyama Shin-Ichiro Kagami Daiki Nakagomi Taro Iwamoto Kei Ikeda Hiroshi Nakajima

RMD Open 9(1) e002770-e002770 2023年2月

Objectives

Spontaneous pneumomediastinum (SPNM) historically has been considered a poor prognostic factor in dermatomyositis/polymyositis patients complicated with interstitial lung disease (ILD). However, there is a lack of actual data regarding...

Epithelial cell-derived cytokine TSLP activates regulatory T cells by enhancing fatty acid uptake

Tadamichi Kasuya Shigeru Tanaka Jun Tamura Keishi Etori Jumpei Shoda Koto Hattori Yusuke Endo Masayuki Kitajima Takahiro Kageyama Taro Iwamoto Masaya Yokota Arifumi Iwata Akira Suto Kotaro Suzuki Harumi Suzuki Steven F. Ziegler Hiroshi Nakajima

Scientific Reports 13(1) 2023年1月

Abstract

Epithelial cells control a variety of immune cells by secreting cytokines to maintain tissue homeostasis on mucosal surfaces. Regulatory T (Treg) cells are essential for immune homeostasis and for preventing tissue inflammation; however,...

Visceral disseminated varicella zoster virus infection during non-intensive maintenance therapy in a patient with systemic lupus erythematosus.

Koto Hattori Shigeru Tanaka Junichi Ishikawa Yoko Yabe Taro Iwamoto Shunsuke Furuta Kei Ikeda Kotaro Suzuki Hiroshi Nakajima

Modern rheumatology case reports 7(1) 57-59 2023年1月

Visceral disseminated varicella zoster virus infection (VD-VZV) is a rare complication in immunocompromised patients. Although systemic lupus erythematosus (SLE) patients have a higher risk of VZV infection, only a few reports describe VD-VZV in S...