Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (MDA5-DM) is frequently complicated with rapidly progressive-interstitial lung disease (RP-ILD). The prognosis of MDA5-DM with RP-ILD is mostly poor despit...
Arifumi Iwata   Yosuke Toda   Hiroki Furuya   Hiroshi Nakajima   
Allergology international : official journal of the Japanese Society of Allergology 2022年12月
Asthma is characterized by increased airway hyperresponsiveness, reversible airflow limitation, and remodeling due to allergic airway inflammation. Asthma has been proposed to be classified into various phenotypes by cluster analyses integrating c...
Arthritis Research & Therapy 24(1) 2022年12月 [査読有り]
Abstract
Objectives
Methotrexate (MTX) is an anchor drug for the treatment of rheumatoid arthritis (RA). However, the precise mechanisms by which MTX stalls RA progression and alleviates the ensuing disease effects remain unknown. The aim of t...
Arthritis Research & Therapy 24(1) 7-7 2022年12月 [査読有り]
Abstract
Background
Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disease which encompasses patients with heterogenous presentation and a wide range of clinical courses. In this study, we aimed to identify potential su...