International Journal of Clinical Oncology 27(9) 1459-1466 Jun 2022
BACKGROUND: With the evolution of personalized medicine in the field of oncology, which includes optimal treatment selection using next-generation sequencing-based companion diagnostic systems and tumor-agnostic treatments according to common biom...
Takafumi Sakuma Masato Nakamura Tetsuhiro Chiba Terunao Iwanaga Motoyasu Kan Ryuta Kojima Junjie Ao Yaojia Ma Hidemi Unozawa Naoto Fujita Kengo Kanayama Hiroaki Kanzaki Keisuke Koroki Kazufumi Kobayashi Ryo Nakagawa Naoya Kanogawa Soichiro Kiyono Takayuki Kondo Tomoko Saito Sadahisa Ogasawara Shingo Nakamoto Ryosuke Muroyama Jun Kato Takashi Kishimoto Naoya Kato
Laboratory investigation; a journal of technical methods and pathology 102(10) 1150-1157 May 2022
Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease worldwide. Patients with NAFLD often suffer steatohepatitis, which can progress to cirrhosis and hepatocellular carcinoma. The presence of visceral obe...
INTRODUCTION: Advanced hepatocellular carcinoma (HCC) with macrovascular invasion (MVI) has the worst prognosis among all phenotypes. This trial aims to evaluate whether treatment with durvalumab, alone or in combination with tremelimumab, plus pa...
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