○○学科

研究分野

ライフサイエンス / 消化器外科学 / 肝胆膵外科

論文

ECM1 and KRT6A are involved in tumor progression and chemoresistance in the effect of dexamethasone on pancreatic cancer.

Yoshiki Shinomiya Yusuke Kouchi Sakurako Harada-Kagitani Takayuki Ishige Shigetsugu Takano Masayuki Ohtsuka Jun-Ichiro Ikeda Takashi Kishimoto

Cancer science 2024年4月

Pancreatic ductal adenocarcinoma (PDAC) has a very poor prognosis. Neoadjuvant chemotherapy is an effective PDAC treatment option, but chemotherapy causes unfavorable side effects. Glucocorticoids (e.g., dexamethasone [DEX]) are administered to re...

Factors affecting nonfunctioning small pancreatic neuroendocrine neoplasms and proposed new treatment strategies.

Susumu Hijioka Daiki Yamashige Minoru Esaki Goro Honda Ryota Higuchi Toshihiko Masui Yasuhiro Shimizu Masayuki Ohtsuka Yusuke Kumamoto Akio Katanuma Naoto Gotohda Hirofumi Akita Michiaki Unno Itaru Endo Yukihiro Yokoyama Suguru Yamada Ippei Matsumoto Takao Ohtsuka Satoshi Hirano Hiroaki Yasuda Manabu Kawai Taku Aoki Masafumi Nakamura Daisuke Hashimoto Toshiki Rikiyama Akihiko Horiguchi Tsutomu Fujii Shugo Mizuno Keiji Hanada Masaji Tani Takashi Hatori Tetsuhide Ito Masataka Okuno Shingo Kagawa Hiroshi Tajima Tatsuya Ishii Motokazu Sugimoto Shunsuke Onoe Hideki Takami Ryoji Takada Takayuki Miura Yusuke Kurita Keiko Kamei Yuko Mataki Kazuichi Okazaki Yoshifumi Takeyama Hiroki Yamaue Sohei Satoi

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2024年4月

BACKGROUND & AIMS: Despite previously reported treatment strategies for nonfunctioning small (≤20 mm) pancreatic neuroendocrine neoplasms (pNENs), uncertainties persist. We aimed to evaluate the surgically resected cases nonfunctioning small pNENs...

The efficacy of bile liquid biopsy in the diagnosis and treatment of biliary tract cancer.

Yoshifumi Miura Hiroshi Ohyama Rintaro Mikata Yosuke Hirotsu Kenji Amemiya Hitoshi Mochizuki Junichiro Ikeda Masayuki Ohtsuka Naoya Kato Masao Omata

Journal of hepato-biliary-pancreatic sciences 2024年3月

BACKGROUND: Diagnosing biliary tract cancer is difficult because endoscopic retrograde cholangiopancreatography (ERCP) is performed fluoroscopically, and the sensitivity of bile cytology is low. Liquid biopsy of bile using targeted sequencing is e...

Genomic Analysis of Undifferentiated Carcinoma of the Pancreas with Squamous Differentiation: A Case Report.

Motoyasu Kan Yusuke Kouchi Hiroshi Ohyama Genki Usui Masaki Fukuyo Shigetsugu Takano Takashi Kishimoto Atsushi Kaneda Masayuki Ohtsuka Naoya Kato

Cureus 16(2) e55175 2024年2月

Pancreatic cancer is an intractable malignancy associated with a dismal prognosis. Undifferentiated carcinoma, a rare subtype, poses a clinical challenge owing to a limited understanding of its molecular characteristics. In this study, we conducte...

Serum elastase-1 predicts malignancy in intraductal papillary mucinous neoplasm of the pancreas.

Takashi Mishima Shigetsugu Takano Tsukasa Takayashiki Satoshi Kuboki Daisuke Suzuki Nozomu Sakai Isamu Hosokawa Takanori Konishi Hitoe Nishino Shinichiro Nakada Yusuke Kouchi Takashi Kishimoto Masayuki Ohtsuka

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2023年12月

BACKGROUND: The indication for surgical resection of intraductal papillary mucinous neoplasms (IPMNs) is defined by imaging features, such as mural nodules. Although carbohydrate antigen (CA) 19-9 was selected as a parameter for worrisome features...