Akira Yanagisawa received his PhD from Nagoya University. He became an Assistant Professor of Nagoya University and an Associate Professor there. In 2001 he moved to Chiba University as a Full Professor. His research interests focus on the development of new synthetic methods using allylic organometallics such as allylic barium reagents and asymmetric synthesis including chiral phosphine·silver(I) complex-catalyzed asymmetric reactions as well as chiral organotin(IV)-catalyzed asymmetric reactions.
Momo Hasegawa   Kazuhiro Yoshida   Akira Yanagisawa   
CHEMISTRY LETTERS 45(3) 294-296 2016年3月 [査読有り]
The enantio- and diastereoselective cross-annulation of cinnamaldehyde (6) and 2,2,2-trifluoroacetophenone (7) was examined to evaluate the performance of newly developed chiral bicyclic imidazolium salts 3 and 4 as catalyst precursors. The reacti...
Akira Yanagisawa   Naoyuki Kushihara   Takuya Sugita   Moe Horiguchi   Kazuki Ida   Kazuhiro Yoshida   
SYNLETT 26(18) 2541-2546 2015年11月 [査読有り]
A catalytic enantioselective Mannich-type reaction of a cyclohexanone-derived alkenyl trichloroacetate with isatin imines was achieved using an (S)-BINOL-derived chiral tin dibromide possessing a 4-tert-butylphenyl group at 3- and 3-positions as t...
A couple of planar-chiral ferrocene-fused 4-pyridone derivatives 2a and 2b were synthesized in enantiomerically pure form by scalable asymmetric transformations. Pyridones 2 are versatile precursors to various ferrocene-fused pyridine derivatives,...
The Barbier-type benzylation of azo compounds with benzylic chlorides was achieved by using reactive barium as the promoter. Various benzylic hydrazines were synthesized from the corresponding benzylic chlorides. The thus-obtained benzylic hydrazi...
The methods of asymmetric α-hydroxylation of carbonyl compounds and their equivalents, affording optically active α-hydroxy carbonyl compounds, are described here. First, enantioselective α-hydroxylation of preformed metal enolates and silyl enol ...
The demand for functionalized aromatic compounds is growing rapidly in many research fields. Therefore, the efficient synthesis of desired aromatic compounds is a critical issue in organic synthesis. In this account, we describe new synthetic appr...