Akira Yanagisawa received his PhD from Nagoya University. He became an Assistant Professor of Nagoya University and an Associate Professor there. In 2001 he moved to Chiba University as a Full Professor. His research interests focus on the development of new synthetic methods using allylic organometallics such as allylic barium reagents and asymmetric synthesis including chiral phosphine·silver(I) complex-catalyzed asymmetric reactions as well as chiral organotin(IV)-catalyzed asymmetric reactions.
Kazushi Hayashi   Kazuhiro Yoshida   Akira Yanagisawa   
JOURNAL OF ORGANIC CHEMISTRY 78(7) 3464-3469 2013年4月 [査読有り]
The selective synthesis of substituted 4-vinylindoles by the ring-closing enyne metathesis (RCEM)/dehydration sequence is reported. In contrast with many known methods in which a pyrrole ring is constructed onto a functionalized benzene precursor,...
Akira Yanagisawa   Kazuhiro Yoshida   
CHEMICAL RECORD 13(1) 117-127 2013年2月 [査読有り][招待有り]
Asymmetric catalysis under almost-neutral reaction conditions is key for the efficient synthesis of optically active polar molecules. We have developed catalytic enantioselective reactions of acyclic or cyclic alkenyl esters by using an (S)-BINOL-...
Akira Yanagisawa   Takuya Jitsukawa   Kazuhiro Yoshida   
Synlett 24(5) 635-639 2013年 [査読有り]
The addition of allylic barium reagents to azo compounds was achieved with high α-regioselectivity. The double-bond geometry of allylic barium reagents was retained throughout the reaction at -78 °C and E- or Z-enriched allylic hydrazines were sel...
Akira Yanagisawa   Naoyuki Kushihara   Takuya Sugita   Kazuhiro Yoshida   
SYNLETT 23(12) 1783-1788 2012年7月 [査読有り]
A catalytic enantioselective aldol reaction of alkenyl esters with isatins was achieved using an (S)-BINOL-derived chiral tin dibromide possessing a 4-tert-butylphenyl group at 3- and 3'-positions as the chiral pre-catalyst in the presence of sodi...
The methods of asymmetric α-hydroxylation of carbonyl compounds and their equivalents, affording optically active α-hydroxy carbonyl compounds, are described here. First, enantioselective α-hydroxylation of preformed metal enolates and silyl enol ...
The demand for functionalized aromatic compounds is growing rapidly in many research fields. Therefore, the efficient synthesis of desired aromatic compounds is a critical issue in organic synthesis. In this account, we describe new synthetic appr...