Kazutaka Sanada Aoi Washio Hiroki Ishikawa Yasushi Yoshida Takashi Mino Masami Sakamoto
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2022年3月
We developed a chiral symmetry breaking method for monoacylated meso diols. The X-ray crystal structure analysis of monoacylated 1,4-anhydroerythritols, meso cyclic diols with a cis configuration, revealed that the O-(p-anisoyl) derivative crystal...
Takumi Nakamura Hiroki Ishikawa Kazuma Ban Yasushi Yoshida Takashi Mino Yoshio Kasashima Masami Sakamoto
CHEMPLUSCHEM 87(1) 2022年1月
Atroposelective resolution for axially chiral nicotinamides was achieved by dynamic chiral salt formation with L-DBTA using six types of nicotinamides that could not be optically resolved by the preferential crystallization method. Kinetic studies...
Asymmetric construction of chiral N,S-acetal skeletons is important because they are widely present in natural products and pharmaceuticals. Halogen-bonding is a unique interaction that has been an organic synthesis focus, although research into c...
Takashi Mino Yohei Fujisawa Shizuki Yoshida Mitsuru Hirama Takumu Akiyama Ryo Saito Yasushi Yoshida Yoshio Kasashima Masami Sakamoto
Organic and Biomolecular Chemistry 19(47) 10385-10389 2021年12月
We synthesized cinnamoyl amide type chiral P,olefin ligand (S)-4. We successfully obtained separable diastereomers of 4d and demonstrated Pd-catalyzed asymmetric allylic substitution reactions of indoles using (S,aS)-4d as a chiral ligand with hig...
大学院国際学術研究院