JOURNAL OF BIOMEDICAL OPTICS 14(5) 054017 2009年9月 [査読有り]
Animal imaging sources have become an indispensable material for biological sciences. Specifically, gene-encoded biological probes serve as stable and high-performance tools to visualize cellular fate in living animals. We use a somatic cell cloni...
Nomoto, T   Okada, T   Shimazaki, K   Yoshioka, T   Nonaka-Sarukawa, M   Ito, T   Takeuchi, K   Katsura, K.I   Mizukami, H   Kume, A   Ookawara, S   Ikeda, U   Katayama, Y   Ozawa, K   
Recombinant adeno-associated virus (AAV) vectors are of interest for cochlear gene therapy because of their ability to mediate the efficient transfer and long-term stable expression of therapeutic genes in a wide variety of postmitotic tissues wit...
Background. The characteristics of adenovirus-mediated gene transfer into the kidney are not well examined. We studied the effects of contact time and temperature on adenovirus-mediated transgene expression in rat kidneys, using catheter-based in ...
Rodent and human clinical studies have shown that transplantation of bone marrow stem cells to the ischemic myocardium results in improved cardiac function. In this study, cynomolgus monkey acute myocardial infarction was generated by ligating the...
Y Ogata   M Takahashi   K Takeuchi   S Ueno   H Mano   S Ookawara   E Kobayashi   U Ikeda   K Shimada   
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 40(6) 907-915 2002年12月
Hydroxymethylglutaryl CoA (HMG-CoA) reductase inhibitors (statins) have been shown to reduce atherosclerotic cardiovascular mortality and morbidity. Recent evidence indicates that statins may also exert direct effects on vascular wall cells (inclu...
JOURNAL OF BIOLOGICAL CHEMISTRY 277(48) 46463-46469 2002年11月
We cloned a rat ABO homologue and established human A- and B-transferase transgenic rats. A DNA fragment corresponding to exon 7 of the human ABO gene was amplified from Wistar rat genomic DNA and sequenced. Using the amplified fragments as a prob...