Akinori Takemura   Sanae Ishii   Yugo Ikeyama   Katsuhiro Esashika   Jun Takahashi   Kousei Ito   
Drug metabolism and pharmacokinetics 52 100511-100511 2023年4月
Drug-induced liver injury (DILI) is a major factor underlying drug withdrawal from the market. Therefore, it is important to predict DILI during the early phase of drug discovery. Metabolic activation and mitochondrial toxicity are good indicators...