Tomohiro Shirayanagi   Shigeki Aoki   Sota Fujimori   Kenji Watanabe   Tetsuo Aida   Makoto Hirasawa   Kazuyoshi Kumagai   Tyuji Hoshino   Kousei Ito   
Biological & pharmaceutical bulletin 43(6) 1007-1015 2020年 [査読有り]
The interaction of human leukocyte antigen (HLA) with specific drugs is associated with delayed-type hypersensitivity reactions, which cause severe cutaneous toxicity. Such interactions induce structural alterations in HLA complexes via several di...