Genomics on drug development
,病原真菌 Pathogenic fungi 酵母 Yeast ゲノム構造 Genome structure ゲノム機能 Genome function ゲノム創薬 Drug development
,Genomics on drug development
,Pathogenic fungi Yeast Genome structure Genome function Drug development
Journal of fungi (Basel, Switzerland) 9(2) 2023年2月 [査読有り]
Mitochondrial dysfunction or morphological abnormalities in human pathogenic fungi are known to contribute to azole resistance; however, the underlying molecular mechanisms are unknown. In this study, we investigated the link between mitochondrial...
<title>Abstract</title>
The circumstances in which organisms live induce polymorphism in their genes, including fungal allergen genes, leading to altered structures and functions of proteins, related to their pathogenicity.<bold> </bold>Major all...
Sandwich freezing is a method of rapid freezing by sandwiching specimens between two metal disks, and has been used for observing exquisite close-to-native ultrastructure of living yeast and bacteria. Recently, this method has been found to be use...
Sandwich freezing is a method of rapid freezing by sandwiching biological specimens between two metal disks and has been used for observing exquisite, close-to-native ultrastructure of living yeast and bacteria after freeze-substitution. This meth...