Genomics on drug development
,病原真菌 Pathogenic fungi 酵母 Yeast ゲノム構造 Genome structure ゲノム機能 Genome function ゲノム創薬 Drug development
,Genomics on drug development
,Pathogenic fungi Yeast Genome structure Genome function Drug development
Frontiers in cell and developmental biology 9 607188-607188 2021年 [査読有り]
Biofilm formation of Candida species is considered to be a pathogenic factor of host infection. Since biofilm formation of Candida glabrata has not been as well studied as that of Candida albicans, we performed genetic screening of C. glabrata, an...
Pedro Pais   Susana Vagueiro   Dalila Mil-Homens   Andreia I Pimenta   Romeu Viana   Michiyo Okamoto   Hiroji Chibana   Arsénio M Fialho   Miguel C Teixeira   
Virulence 11(1) 1522-1538 2020年12月 [査読有り]
Candida glabrata is a prominent pathogenic yeast which exhibits a unique ability to survive the harsh environment of host immune cells. In this study, we describe the role of the transcription factor encoded by the gene CAGL0F09229g, here named Cg...
Frontiers in Microbiology 11 607795-607795 2020年12月 [査読有り]
The filamentous fungal pathogen <italic>Aspergillus fumigatus</italic> is one of the most common causal agents of invasive fungal infection in humans; the infection is associated with an alarmingly high mortality rate. In this study, we investigat...
In 2012, we discovered a unique microorganism (Parakaryon myojinensis) that has intermediate cellular structures between prokaryotes and eukaryotes from the deep sea off the coast of Japan. Observations of ultrathin sections of deep-sea specimens ...